Tinyatoxin
Encyclopedia
Tinyatoxin is a highly irritable analog of resiniferatoxin
and capsaicin
. It is a neurotoxin and (like its analogs) acts via vanilloid
receptors of sensory nerves. Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin
. Tinyatoxin is about three times weaker than resiniferatoxin.
Resiniferatoxin
Resiniferatoxin is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception...
and capsaicin
Capsaicin
Capsaicin 2CHCH=CH4CONHCH2C6H3-4--3- ) is the active component of chili peppers, which are plants belonging to the genus Capsicum. It is an irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact...
. It is a neurotoxin and (like its analogs) acts via vanilloid
Vanillyl
In organic chemistry, vanillyl is a functional group. Compounds containing a vanillyl group are called vanilloids, and include vanillin, vanillic acid, capsaicin and VMA....
receptors of sensory nerves. Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin
Capsaicin
Capsaicin 2CHCH=CH4CONHCH2C6H3-4--3- ) is the active component of chili peppers, which are plants belonging to the genus Capsicum. It is an irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact...
. Tinyatoxin is about three times weaker than resiniferatoxin.