Thymosin beta-4, Y-chromosomal
Encyclopedia
Thymosin beta-4, Y-chromosomal is a protein
that in humans is encoded by the TMSB4Y gene
.
The protein consists (in humans) of 44 amino acid
s (msdkpgmaei ekfdksklkk tetqeknpls sketieqerq ages) MolWt 4881.
. Its homolog on chromosome X
(thymosin beta-4) escapes X inactivation and encodes an actin
sequestering protein.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the TMSB4Y gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
The protein consists (in humans) of 44 amino acid
Amino acid
Amino acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen...
s (msdkpgmaei ekfdksklkk tetqeknpls sketieqerq ages) MolWt 4881.
Function
This gene lies within the male specific region of chromosome YY chromosome
The Y chromosome is one of the two sex-determining chromosomes in most mammals, including humans. In mammals, it contains the gene SRY, which triggers testis development if present. The human Y chromosome is composed of about 60 million base pairs...
. Its homolog on chromosome X
X chromosome
The X chromosome is one of the two sex-determining chromosomes in many animal species, including mammals and is common in both males and females. It is a part of the XY sex-determination system and X0 sex-determination system...
(thymosin beta-4) escapes X inactivation and encodes an actin
Actin
Actin is a globular, roughly 42-kDa moonlighting protein found in all eukaryotic cells where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans...
sequestering protein.