Tetrazolylglycine
Encyclopedia
Tetrazolylglycine is a potent and selective NMDA receptor
agonist
, stimulating the NMDA receptor with higher potency than either glutamate or NMDA
. It is a potent convulsant
and excitotoxin and is used in scientific research.
NMDA receptor
The NMDA receptor , a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function....
agonist
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
, stimulating the NMDA receptor with higher potency than either glutamate or NMDA
NMDA
N-Methyl-D-aspartic acid or N-Methyl-D-aspartate is an amino acid derivative which acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor...
. It is a potent convulsant
Convulsant
A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant. These drugs generally act as stimulants at low doses, but are not used for this purpose due to the risk of convulsions and consequent excitotoxicity...
and excitotoxin and is used in scientific research.