Testosterone undecanoate
Encyclopedia
Testosterone undecanoate or testosterone undecylate is an ester of testosterone
Testosterone
Testosterone is a steroid hormone from the androgen group and is found in mammals, reptiles, birds, and other vertebrates. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands...

 which is used for the treatment of male hypogonadism
Hypogonadism
Hypogonadism is a medical term for decreased functional activity of the gonads. Low testosterone is caused by a decline or deficiency in gonadal production of testosterone in males...

, and is currently under research for use as a male contraceptive
Male contraceptive
Male contraceptives include condoms, withdrawal , and vasectomy. In other animals, castration is commonly used for contraception...

. It is sold and distributed under the brand names Andriol, Undestor, Nebido, Pantestone, Restandol, Cernos Depot and Nebido-R and Reandron 1000.

Andriol is a version of the anabolic steroid testosterone undecanoate developed by the pharmaceutical company Organon. This testosterone preparation is encapsulated and sealed in an oil base in a 40 mg capsule taken orally. According to Organon, this method bypasses the liver, preventing it from being damaged by the liver and from adding damaging stresses to the liver found in other testosterone preparations. It is said to enter the body as a fat through the lymphatic system. Experience from users indicates that in doses of less than 240 mg per day, effects are negligible, except at the very onset of use, while even in higher doses, effects are still minimal. It is therefore thought that most of the steroid is somehow not making it into the blood stream.
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