Tenascin-R
Encyclopedia
Tenascin-R is a protein
that in humans is encoded by the TNR gene
.
protein expressed primarily in the central nervous system. It is a member of the tenascin
(TN) gene family, which includes at least 3 genes in mammals: TNC
(or hexabrachion), TNX
(TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.[supplied by OMIM]
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the TNR gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
Tenascin-R (TNR) is an extracellular matrixExtracellular matrix
In biology, the extracellular matrix is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. The extracellular matrix is the defining feature of connective tissue in animals.Extracellular...
protein expressed primarily in the central nervous system. It is a member of the tenascin
Tenascin
Tenascins are extracellular matrix glycoproteins. They are abundant in the extracellular matrix of developing vertebrate embryos and they reappear around healing wounds and in the stroma of some tumors.-Types:...
(TN) gene family, which includes at least 3 genes in mammals: TNC
Tenascin C
Tenascin is a protein that in humans is encoded by the TNC gene.-Interactions:Tenascin C has been shown to interact with fibronectin.-Further reading:...
(or hexabrachion), TNX
Tenascin X
A member of the tenascin family, tenascin X also known as hexabrachion-like protein is a glycoprotein that is expressed in connective tissues including skin, joints and muscles. In humans, tenascin X is encoded by the TNXB gene.- Gene :...
(TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.[supplied by OMIM]