Taste receptor
Encyclopedia
A Taste receptor is a type of receptor
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...

 which facilitates the sensation of taste
Taste
Taste is one of the traditional five senses. It refers to the ability to detect the flavor of substances such as food, certain minerals, and poisons, etc....

.

Examples include TAS2R16
TAS2R16
TAS2R16 is a human gene that encodes for a receptor that may play a role in the perception of bitterness...

 and TAS2R38
TAS2R38
TAS2R38 is a bitter taste receptor which facilitates the tasting of phenylthiocarbamide and propylthiouracil , although it does not explain supertasting.. Carriers of the PAV allele experience more bitterness from vegetables and consume vegetables less frequently and in lower amounts ....

.

They are divided into two families:
  • Type 1, sweet
    Sweetness
    Sweetness is one of the five basic tastes and is almost universally regarded as a pleasurable experience. Foods rich in simple carbohydrates such as sugar are those most commonly associated with sweetness, although there are other natural and artificial compounds that are sweet at much lower...

    , first characterized in 2001: –
  • Type 2, bitter, first characterized in 2000: – , and


Human bitter taste receptor genes are named TAS2R1 to TAS2R64, with many gaps due to non-existent genes, pseudogenes or proposed genes that have not been annotated to the most recent human genome assembly. Many bitter taste receptor genes also have confusing synonym names with several different gene names referring to the same gene. See table below for full list of human bitter taste receptor genes:
Class Gene Synonyms Aliases Locus Description
type 1
(sweet)
TAS1R1
TAS1R1
Taste receptor type 1 member 1 is a protein that in humans is encoded by the TAS1R1 gene.-Further reading:...

GPR70 1p36.23
TAS1R2
TAS1R2
Taste receptor type 1 member 2 is a protein that in humans is encoded by the TAS1R2 gene.A mutation in this gene gives cats the inability to taste sugar.-Further reading:...

GPR71 1p36.23
TAS1R3
TAS1R3
Taste receptor type 1 member 3 is a protein that in humans is encoded by the TAS1R3 gene.-Further reading:...

1p36
type 2
(bitter)
TAS2R1
TAS2R1
Taste receptor type 2 member 1 is a protein that in humans is encoded by the TAS2R1 gene.-Further reading:...

5p15
TAS2R2 7p21.3 pseudogene
TAS2R3
TAS2R3
Taste receptor type 2 member 3 is a protein that in humans is encoded by the TAS2R3 gene.-Further reading:...

7q31.3-q32
TAS2R4
TAS2R4
Taste receptor type 2 member 4 is a protein that in humans is encoded by the TAS2R4 gene.-Further reading:...

7q31.3-q32
TAS2R5
TAS2R5
Taste receptor type 2 member 5 is a protein that in humans is encoded by the TAS2R5 gene.-Further reading:...

7q31.3-q32
TAS2R6 7 not annotated in human genome assembly
TAS2R7
TAS2R7
Taste receptor type 2 member 7 is a protein that in humans is encoded by the TAS2R7 gene.-Further reading:...

12p13
TAS2R8
TAS2R8
Taste receptor type 2 member 8 is a protein that in humans is encoded by the TAS2R8 gene.-Further reading:...

12p13
TAS2R9
TAS2R9
Taste receptor type 2 member 9 is a protein that in humans is encoded by the TAS2R9 gene.-Further reading:...

12p13
TAS2R10
TAS2R10
Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene.-Further reading:...

12p13
TAS2R11 absent in humans
TAS2R12 12p13.2 pseudogene
TAS2R13
TAS2R13
Taste receptor type 2 member 13 is a protein that in humans is encoded by the TAS2R13 gene.-Further reading:...

12p13
TAS2R14
TAS2R14
Taste receptor type 2 member 14 is a protein that in humans is encoded by the TAS2R14 gene.- Function :This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor...

12p13
TAS2R15 12p13.2 pseudogene
TAS2R16
TAS2R16
TAS2R16 is a human gene that encodes for a receptor that may play a role in the perception of bitterness...

7q31.1-q31.3
TAS2R17 absent in humans
TAS2R18 12p13.2 pseudogene
TAS2R19 TAS2R23, TAS2R48 12p13.2
TAS2R20 TAS2R49 12p13.2
TAS2R21 absent in humans
TAS2R22 12 not annotated in human genome assembly
TAS2R24 absent in humans
TAS2R25 absent in humans
TAS2R26 pseudogene
TAS2R27 absent in humans
TAS2R28 absent in humans
TAS2R29 absent in humans
TAS2R30 TAS2R47 12p13.2
TAS2R31 TAS2R44 12p13.2
TAS2R32 absent in humans
TAS2R33 12 not annotated in human genome assembly
TAS2R34 absent in humans
TAS2R35 absent in humans
TAS2R36 12 not annotated in human genome assembly
TAS2R37 12 not annotated in human genome assembly
TAS2R38
TAS2R38
TAS2R38 is a bitter taste receptor which facilitates the tasting of phenylthiocarbamide and propylthiouracil , although it does not explain supertasting.. Carriers of the PAV allele experience more bitterness from vegetables and consume vegetables less frequently and in lower amounts ....

7q34
TAS2R39
TAS2R39
Taste receptor type 2 member 39 is a protein that in humans is encoded by the TAS2R39 gene.-Further reading:...

7q34
TAS2R40
TAS2R40
Taste receptor type 2 member 40 is a protein that in humans is encoded by the TAS2R40 gene.-Further reading:...

GPR60 7q34
TAS2R41
TAS2R41
Taste receptor type 2 member 41 is a protein that in humans is encoded by the TAS2R41 gene.-Further reading:...

7q34
TAS2R42
TAS2R42
Taste receptor, type 2, member 42 is a protein that in humans is encoded by the TAS2R42 gene....

12p13
TAS2R43
TAS2R43
Taste receptor type 2 member 43 is a protein that in humans is encoded by the TAS2R43 gene.-Further reading:...

12p13.2
TAS2R45
TAS2R45
Taste receptor type 2 member 45 is a protein that in humans is encoded by the TAS2R45 gene.-Further reading:...

GPR59 12
TAS2R46
TAS2R46
Taste receptor type 2 member 46 is a protein that in humans is encoded by the TAS2R46 gene.-Further reading:...

12p13.2
TAS2R50
TAS2R50
Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene.-Further reading:...

TAS2R51 12p13.2
TAS2R50 absent in humans
TAS2R51 absent in humans
TAS2R52 absent in humans
TAS2R53 absent in humans
TAS2R54 absent in humans
TAS2R55 absent in humans
TAS2R56 absent in humans
TAS2R57 absent in humans
TAS2R58 absent in humans
TAS2R59 absent in humans
TAS2R60
TAS2R60
Taste receptor type 2 member 60 is a protein that in humans is encoded by the TAS2R60 gene.-Further reading:...

7
TAS2R62P 7q34 pseudogene
TAS2R63P 12p13.2 pseudogene
TAS2R64P 12p13.2 pseudogene
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