Taste receptor
Encyclopedia
A Taste receptor is a type of receptor
which facilitates the sensation of taste
.
Examples include TAS2R16
and TAS2R38
.
They are divided into two families:
Human bitter taste receptor genes are named TAS2R1 to TAS2R64, with many gaps due to non-existent genes, pseudogenes or proposed genes that have not been annotated to the most recent human genome assembly. Many bitter taste receptor genes also have confusing synonym names with several different gene names referring to the same gene. See table below for full list of human bitter taste receptor genes:
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
which facilitates the sensation of taste
Taste
Taste is one of the traditional five senses. It refers to the ability to detect the flavor of substances such as food, certain minerals, and poisons, etc....
.
Examples include TAS2R16
TAS2R16
TAS2R16 is a human gene that encodes for a receptor that may play a role in the perception of bitterness...
and TAS2R38
TAS2R38
TAS2R38 is a bitter taste receptor which facilitates the tasting of phenylthiocarbamide and propylthiouracil , although it does not explain supertasting.. Carriers of the PAV allele experience more bitterness from vegetables and consume vegetables less frequently and in lower amounts ....
.
They are divided into two families:
- Type 1, sweetSweetnessSweetness is one of the five basic tastes and is almost universally regarded as a pleasurable experience. Foods rich in simple carbohydrates such as sugar are those most commonly associated with sweetness, although there are other natural and artificial compounds that are sweet at much lower...
, first characterized in 2001: – - Type 2, bitter, first characterized in 2000: – , and
Human bitter taste receptor genes are named TAS2R1 to TAS2R64, with many gaps due to non-existent genes, pseudogenes or proposed genes that have not been annotated to the most recent human genome assembly. Many bitter taste receptor genes also have confusing synonym names with several different gene names referring to the same gene. See table below for full list of human bitter taste receptor genes:
Class | Gene | Synonyms | Aliases | Locus | Description |
---|---|---|---|---|---|
type 1 (sweet) |
TAS1R1 TAS1R1 Taste receptor type 1 member 1 is a protein that in humans is encoded by the TAS1R1 gene.-Further reading:... |
GPR70 | 1p36.23 | ||
TAS1R2 TAS1R2 Taste receptor type 1 member 2 is a protein that in humans is encoded by the TAS1R2 gene.A mutation in this gene gives cats the inability to taste sugar.-Further reading:... |
GPR71 | 1p36.23 | |||
TAS1R3 TAS1R3 Taste receptor type 1 member 3 is a protein that in humans is encoded by the TAS1R3 gene.-Further reading:... |
1p36 | ||||
type 2 (bitter) |
TAS2R1 TAS2R1 Taste receptor type 2 member 1 is a protein that in humans is encoded by the TAS2R1 gene.-Further reading:... |
5p15 | |||
TAS2R2 | 7p21.3 | pseudogene | |||
TAS2R3 TAS2R3 Taste receptor type 2 member 3 is a protein that in humans is encoded by the TAS2R3 gene.-Further reading:... |
7q31.3-q32 | ||||
TAS2R4 TAS2R4 Taste receptor type 2 member 4 is a protein that in humans is encoded by the TAS2R4 gene.-Further reading:... |
7q31.3-q32 | ||||
TAS2R5 TAS2R5 Taste receptor type 2 member 5 is a protein that in humans is encoded by the TAS2R5 gene.-Further reading:... |
7q31.3-q32 | ||||
TAS2R6 | 7 | not annotated in human genome assembly | |||
TAS2R7 TAS2R7 Taste receptor type 2 member 7 is a protein that in humans is encoded by the TAS2R7 gene.-Further reading:... |
12p13 | ||||
TAS2R8 TAS2R8 Taste receptor type 2 member 8 is a protein that in humans is encoded by the TAS2R8 gene.-Further reading:... |
12p13 | ||||
TAS2R9 TAS2R9 Taste receptor type 2 member 9 is a protein that in humans is encoded by the TAS2R9 gene.-Further reading:... |
12p13 | ||||
TAS2R10 TAS2R10 Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene.-Further reading:... |
12p13 | ||||
TAS2R11 | absent in humans | ||||
TAS2R12 | 12p13.2 | pseudogene | |||
TAS2R13 TAS2R13 Taste receptor type 2 member 13 is a protein that in humans is encoded by the TAS2R13 gene.-Further reading:... |
12p13 | ||||
TAS2R14 TAS2R14 Taste receptor type 2 member 14 is a protein that in humans is encoded by the TAS2R14 gene.- Function :This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor... |
12p13 | ||||
TAS2R15 | 12p13.2 | pseudogene | |||
TAS2R16 TAS2R16 TAS2R16 is a human gene that encodes for a receptor that may play a role in the perception of bitterness... |
7q31.1-q31.3 | ||||
TAS2R17 | absent in humans | ||||
TAS2R18 | 12p13.2 | pseudogene | |||
TAS2R19 | TAS2R23, TAS2R48 | 12p13.2 | |||
TAS2R20 | TAS2R49 | 12p13.2 | |||
TAS2R21 | absent in humans | ||||
TAS2R22 | 12 | not annotated in human genome assembly | |||
TAS2R24 | absent in humans | ||||
TAS2R25 | absent in humans | ||||
TAS2R26 | pseudogene | ||||
TAS2R27 | absent in humans | ||||
TAS2R28 | absent in humans | ||||
TAS2R29 | absent in humans | ||||
TAS2R30 | TAS2R47 | 12p13.2 | |||
TAS2R31 | TAS2R44 | 12p13.2 | |||
TAS2R32 | absent in humans | ||||
TAS2R33 | 12 | not annotated in human genome assembly | |||
TAS2R34 | absent in humans | ||||
TAS2R35 | absent in humans | ||||
TAS2R36 | 12 | not annotated in human genome assembly | |||
TAS2R37 | 12 | not annotated in human genome assembly | |||
TAS2R38 TAS2R38 TAS2R38 is a bitter taste receptor which facilitates the tasting of phenylthiocarbamide and propylthiouracil , although it does not explain supertasting.. Carriers of the PAV allele experience more bitterness from vegetables and consume vegetables less frequently and in lower amounts .... |
7q34 | ||||
TAS2R39 TAS2R39 Taste receptor type 2 member 39 is a protein that in humans is encoded by the TAS2R39 gene.-Further reading:... |
7q34 | ||||
TAS2R40 TAS2R40 Taste receptor type 2 member 40 is a protein that in humans is encoded by the TAS2R40 gene.-Further reading:... |
GPR60 | 7q34 | |||
TAS2R41 TAS2R41 Taste receptor type 2 member 41 is a protein that in humans is encoded by the TAS2R41 gene.-Further reading:... |
7q34 | ||||
TAS2R42 TAS2R42 Taste receptor, type 2, member 42 is a protein that in humans is encoded by the TAS2R42 gene.... |
12p13 | ||||
TAS2R43 TAS2R43 Taste receptor type 2 member 43 is a protein that in humans is encoded by the TAS2R43 gene.-Further reading:... |
12p13.2 | ||||
TAS2R45 TAS2R45 Taste receptor type 2 member 45 is a protein that in humans is encoded by the TAS2R45 gene.-Further reading:... |
GPR59 | 12 | |||
TAS2R46 TAS2R46 Taste receptor type 2 member 46 is a protein that in humans is encoded by the TAS2R46 gene.-Further reading:... |
12p13.2 | ||||
TAS2R50 TAS2R50 Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene.-Further reading:... |
TAS2R51 | 12p13.2 | |||
TAS2R50 | absent in humans | ||||
TAS2R51 | absent in humans | ||||
TAS2R52 | absent in humans | ||||
TAS2R53 | absent in humans | ||||
TAS2R54 | absent in humans | ||||
TAS2R55 | absent in humans | ||||
TAS2R56 | absent in humans | ||||
TAS2R57 | absent in humans | ||||
TAS2R58 | absent in humans | ||||
TAS2R59 | absent in humans | ||||
TAS2R60 TAS2R60 Taste receptor type 2 member 60 is a protein that in humans is encoded by the TAS2R60 gene.-Further reading:... |
7 | ||||
TAS2R62P | 7q34 | pseudogene | |||
TAS2R63P | 12p13.2 | pseudogene | |||
TAS2R64P | 12p13.2 | pseudogene |