TLE1
Encyclopedia
Transducin-like enhancer protein 1 is a protein
that in humans is encoded by the TLE1 gene
.
with TLE2
, Glycoprotein 130
, UTY
, HES6
, RUNX3
, SIX3
and RUNX1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the TLE1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
TLE1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with TLE2
TLE2
Transducin-like enhancer protein 2 is a protein that in humans is encoded by the TLE2 gene.-Interactions:TLE2 has been shown to interact with TLE1 and HES1.-Further reading:...
, Glycoprotein 130
Glycoprotein 130
Glycoprotein 130 is a transmembrane protein which is the founding member of the class of all cytokine receptors. It forms one subunit of type I cytokine receptors within the IL-6 receptor family...
, UTY
UTY (gene)
Histone demethylase UTY is an enzyme that in humans is encoded by the UTY gene.-Interactions:UTY has been shown to interact with TLE1.-Further reading:...
, HES6
HES6
Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene....
, RUNX3
RUNX3
Runt-related transcription factor 3 is a protein that in humans is encoded by the RUNX3 gene.- Knockout mouse :Runx3 null mouse gastric mucosa exhibits hyperplasia due to stimulated proliferation and suppressed apoptosis in epithelial cells, and the cells are resistant to TGF-beta...
, SIX3
SIX3
Homeobox protein SIX3 is a protein that in humans is encoded by the SIX3 gene.-Interactions:SIX3 has been shown to interact with TLE1 and Neuron-derived orphan receptor 1.-External links:*...
and RUNX1
RUNX1
Runt-related transcription factor 1 also known as acute myeloid leukemia 1 protein or core-binding factor subunit alpha-2 is a protein that in humans is encoded by the RUNX1 gene....
.