Synpolydactyly
Encyclopedia
Synpolydactyly is a joint presentation of syndactyly
and polydactyly
.
Types include:
Syndactyly
Syndactyly is a condition wherein two or more digits are fused together. It occurs normally in some mammals, such as the siamang and kangaroo, but is an unusual condition in humans.-Classification:...
and polydactyly
Polydactyly
Polydactyly or polydactylism , also known as hyperdactyly, is a congenital physical anomaly in humans, dogs, and cats having supernumerary fingers or toes....
.
Types include:
| OMIM | Name | Gene |
|---|---|---|
| SPD1 | HOXD13 HOXD13 Homeobox protein Hox-D13 is a protein that in humans is encoded by the HOXD13 gene.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms... |
|
| SPD2 | FBLN1 FBLN1 FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein.- Function :Fibulin-1 is a secreted glycoprotein that is found in association with extracellular matrix structures including fibronectin-containing fibers, elastin-containing fibers and basement membranes... |
|
| SPD3 | ? at 14q11.2-q12 |