Sup45p is the Saccharomyces cerevisiae

Saccharomyces cerevisiae

Saccharomyces cerevisiae is a species of yeast. It is perhaps the most useful yeast, having been instrumental to baking and brewing since ancient times. It is believed that it was originally isolated from the skin of grapes...

 (a yeast) eukaryotic translation termination factor. More specifically, it is the yeast eukaryotic release factor 1 (eRF1). Its job is to recognize stop codons in RNA

RNA

Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....

 and bind to them. It binds to the Sup35p

Sup35p

Sup35p is the Saccharomyces cerevisiae eukaryotic translation release factor. More specifically, it is the yeast eukaryotic release factor 3 , which forms the translation termination complex with eRF1 . This complex recognizes and catalyzes the release of the nascent polypeptide chain when the...

 protein and then takes on the shape of a tRNA molecule so that it can safety incorporate itself into the A site of the Ribosome

Ribosome

A ribosome is a component of cells that assembles the twenty specific amino acid molecules to form the particular protein molecule determined by the nucleotide sequence of an RNA molecule....

to disruptits flow and "release" the protein and end translation.