Streptogramin
Encyclopedia
Streptogramins are a class of antibiotics.
Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus
(VRSA) and vancomycin-resistant Enterococcus
(VRE), two of the most rapidly-growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A
and streptogramin B
.
Members include:
Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus
Vancomycin-resistant Staphylococcus aureus
Vancomycin-resistant Staphylococcus aureus refers to strains of Staphylococcus aureus that have become resistant to the glycopeptide antibiotic vancomycin. With the increase of staphylococcal resistance to methicillin, vancomycin is often a treatment of choice in infections with...
(VRSA) and vancomycin-resistant Enterococcus
Vancomycin-Resistant Enterococcus
Vancomycin-resistant Enterococcus, or vancomycin-resistant enterococci , are bacterial strains of the genus Enterococcus that are resistant to the antibiotic vancomycin. To become VRE, vancomycin-sensitive enterococci typically obtain new DNA in the form of plasmids or transposons which encode...
(VRE), two of the most rapidly-growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A
Streptogramin A
Streptogramin A is group of antibiotics within the larger family of antibiotics known as streptogramins. They are synthesized by the bacteria Streptomyces virginiae...
and streptogramin B
Streptogramin B
Streptogramin B is a subgroup of the streptogramin antibiotics family. These natural products are cyclic hexa- or hepta depsipeptides produced by various members of the genus of bacteria Streptomyces...
.
Members include:
- Quinupristin/dalfopristinQuinupristin/dalfopristinQuinupristin/dalfopristin is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium....
- PristinamycinPristinamycinPristinamycin , also spelled pristinamycine, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. It is a streptogramin group antibiotic, similar to virginiamycin, derived from the bacterium Streptomyces pristinaespiralis...
- VirginiamycinVirginiamycinVirginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent microbial contamination...
- NXL 103, an experimental streptogramin in clinical trials for the treatment of respiratory tract infections.