St. Mark's Hospital
Encyclopedia
St. Mark's Hospital is a hospital in the Harrow
Harrow, London
Harrow is an area in the London Borough of Harrow, northwest London, United Kingdom. It is a suburban area and is situated 12.2 miles northwest of Charing Cross...

 and Wembley
Wembley
Wembley is an area of northwest London, England, and part of the London Borough of Brent. It is home to the famous Wembley Stadium and Wembley Arena...

 border as well as the London Borough of Harrow
London Borough of Harrow
The London Borough of Harrow is a London borough of north-west London. It borders Hertfordshire to the north and other London boroughs: Hillingdon to the west, Ealing to the south, Brent to the south-east and Barnet to the east.-History:...

 and London Borough of Brent
London Borough of Brent
In 1801, the civil parishes that form the modern borough had a total population of 2,022. This rose slowly throughout the 19th century, as the district became built up; reaching 5,646 in the middle of the century. When the railways arrived the rate of population growth increased...

 border in northwest London
London
London is the capital city of :England and the :United Kingdom, the largest metropolitan area in the United Kingdom, and the largest urban zone in the European Union by most measures. Located on the River Thames, London has been a major settlement for two millennia, its history going back to its...

, UK. It is the only hospital in the world to specialise entirely in intestinal and colorectal medicine and is a national and international referral centre for intestinal and colorectal disorders. It is the only hospital in the UK, and one of only 14 worldwide, to be recognised as a centre of excellence by the World Organisation of Digestive Endoscopy.

St. Mark's is closely associated with Imperial College London
Imperial College London
Imperial College London is a public research university located in London, United Kingdom, specialising in science, engineering, business and medicine...

 and is a major centre for teaching and research.

Beginnings

The beginnings of St Mark's Hospital were in a small room at No 11 Aldersgate Street where, in 1835, Frederick Salmon opened 'The Infirmary for the Relief of the Poor afflicted with Fistula and other Diseases of the Rectum'. There were just seven beds and in the first year 131 patients were admitted. Frederick Salmon was born in Bath in 1796 and served his apprenticeship in medicine there. He qualified at St Bartholomew's Hospital in 1817 and subsequently became a house-surgeon. In 1827, he was elected to a Surgeon's post at the Aldersgate Street Dispensary. However, Salmon resigned five years later, along with the rest of the medical staff, because of a dispute with the Management Committee about the method of choosing new staff. Tired of the restrictions of working within the establishment, Salmon decided to found his own institution to provide treatment for those conditions which were regarded as 'the most distressing that can afflict our common nature'. So the 'Fistula Infirmary', as it came to be known, was started. Much of the financial support came from the City of London. The Lord Mayor, William Taylor Copeland
William Taylor Copeland
William Taylor Copeland, MP, Alderman was a British businessman and politician who served as Lord Mayor of London and a Member of Parliament.- Family and business :...

, was a grateful patient of Salmon's and became the first President. Another benefactor was Charles Dickens
Charles Dickens
Charles John Huffam Dickens was an English novelist, generally considered the greatest of the Victorian period. Dickens enjoyed a wider popularity and fame than had any previous author during his lifetime, and he remains popular, having been responsible for some of English literature's most iconic...

, who blamed his need for Salmon's surgical attentions on 'too much sitting at my desk'! There was an overwhelming need for such an institution giving specialist treatment free of charge to London's poor. Therefore, in 1838, when the number of patients had trebled, Salmon moved to larger premises at 38 Charterhouse Square, where there were fourteen beds and more space for treating out-patients. Thirteen years later, a site in City Road was purchased from the Dyers' Company and the almshouses that occupied it were converted to a twenty-five bed hospital. This was opened on St Mark's Day, 25 April 1854, and took the name of St Mark's Hospital for Fistula and other Diseases of the Rectum. The staff consisted of a surgeon, a Matron, a dispenser, nurses and servants. St Mark's was unique in not employing a physician until 1948. (That all changed in 1950, with the arrival of Francis Avery-Jones, “the father of British gastroenterology”, pioneer of medical treatment of peptic ulcer
Peptic ulcer
A peptic ulcer, also known as PUD or peptic ulcer disease, is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is defined as mucosal erosions equal to or greater than 0.5 cm...

 ) In 1859, Frederick Salmon resigned from his post as Surgeon. He is said to have performed 3,500 operations without a single fatality, a remarkable feat in an age when anaesthetics were only just beginning to be used and antiseptics were unknown. The Governors commissioned a portrait of him which is now displayed outside of the ward that bares his name.

New St Mark’s

By the 1870s, ever-increasing demands on the Hospital caused rebuilding to be considered. The adjacent site, occupied by rice mills, was acquired but could not be developed for some years due to lack of funds. Eventually, building began and in January 1896 the 'New St Mark's' was opened. There was considerable difficulty in meeting the costs of maintaining the new building and it was the entertainment industry that finally came to the rescue. Lillie Langtry
Lillie Langtry
Lillie Langtry , usually spelled Lily Langtry when she was in the U.S., born Emilie Charlotte Le Breton, was a British actress born on the island of Jersey...

 organised a Charity Matinee at her theatre in Drury Lane
Drury Lane
Drury Lane is a street on the eastern boundary of the Covent Garden area of London, running between Aldwych and High Holborn. The northern part is in the borough of Camden and the southern part in the City of Westminster....

 and the Hospital was saved. In 1909, the name of the Hospital was changed for a second time to St Mark's Hospital for Cancer, Fistula etc., reflecting the work and interests of Lockhart-Mummery, who was a pioneer in cancer surgery. The First World War seems to have made little direct impact, although ten beds were given over to servicemen. Despite the stringency of the times, the Governors purchased more land on the east side of the Hospital which gave room for expansion after hostilities had ceased. An Appeal Fund launched in 1920 which was very successful. In 1926 work began on a large extension which gave the Hospital a new appearance and provided two new wards, as well as new Out-Patient, X-ray, Pathology and Research Departments. A nurses' home was also provided for the first time. This was replaced by a self-contained home in 1936, when the former accommodation became a private wing named after Lockhart-Mummery, who had retired the previous year. A Samaritan Fund was established to assist patients, and meetings ceased in May 1949 when administration of the Fund officially passed to the Ladies Association. The Ladies Association became the Friends of St Mark's in June 1971.

1948 to present

St Mark's was taken over by the new National Health Service
National Health Service
The National Health Service is the shared name of three of the four publicly funded healthcare systems in the United Kingdom. They provide a comprehensive range of health services, the vast majority of which are free at the point of use to residents of the United Kingdom...

 in 1948. It was administered jointly with Hammersmith Hospital
Hammersmith Hospital
Hammersmith Hospital is a major teaching hospital in West London. It is part of Imperial College Healthcare NHS Trust in the London Borough of Hammersmith and Fulham, and is associated with the Imperial College Faculty of Medicine...

 until the NHS reforms of 1972, when it became attached to St Bartholomew's Hospital
St Bartholomew's Hospital
St Bartholomew's Hospital, also known as Barts, is a hospital in Smithfield in the City of London, England.-Early history:It was founded in 1123 by Raherus or Rahere , a favourite courtier of King Henry I...

. After 1974, St Mark's was part of the newly-established City and Hackney Health District, which also included Hackney General, the Mothers', the German, the Eastern and St Leonard's Hospitals. During the 1980s, many of the hospitals in the City and Hackney District were closed and their services transferred to the new Homerton Hospital. The government introduced self-governing NHS Trusts and in 1992, Sir Bernard Tomlinson's Report of the Inquiry into the London Health Service proposed radical changes to the hospital groupings then in place. St Mark's remained part of the Barts NHS Shadow Trust (later Barts NHS Group) until April 1994, when the changes envisaged by the Tomlinson Report came into force. At this point, Bart's joined with the Royal London
Royal London Hospital
The Royal London Hospital was founded in September 1740 and was originally named The London Infirmary. The name changed to The London Hospital in 1748 and then to The Royal London Hospital on its 250th anniversary in 1990. The first patients were treated at a house in Featherstone Street,...

 and the London Chest Hospital
London Chest Hospital
The London Chest Hospital, located in Bethnal Green in London, adjacent to Victoria Park, is a hospital run by the Barts and the London NHS Trust. It was founded in 1848, and first opened in 1855....

s to form the Royal Hospitals NHS Trust (later Barts and The London NHS Trust
Barts and The London NHS Trust
Barts and The London NHS Trust is an NHS Trust operating in the City of London and east London.It runs three hospitals:* The Royal London Hospital in Whitechapel* St Bartholomew's Hospital in Smithfield in the City...

). St Mark's became part of the North West London NHS trust and moved to the same site as Northwick Park Hospital
Northwick Park Hospital
Northwick Park Hospital is a large hospital in the northwest corner of the London Borough of Brent in Greater London, England.-Hospital role:...

. The hospital maintains strong teaching ties with Imperial College School of Medicine
Imperial College School of Medicine
The Imperial College School of Medicine is the medical school of Imperial College London in England, and one of the United Hospitals....

.

Centre of excellence

Following are highlights of the achievements made at the hospital over the years:
  • The Lockhart-Mummery technique was developed at St Mark’s in the early 1900s by the pioneering cancer surgeon whose name it bears.
  • The ‘Dukes’ staging system, still in use, was developed at St Mark’s by Cuthbert Dukes
    Cuthbert Dukes
    Cuthbert Esquire Dukes, M.D. OBE was an English physician and pathologist and author for whom the Dukes classification for colorectal cancer is named....

     who worked there from around 1920 till 1950.
  • David Henry Goodsall 1843–1906 who described Goodsall's rule
    Goodsall's rule
    Goodsall's rule relates the external opening of an anal fistula to its internal opening. It states that the external opening situated behind the transverse anal line will open into the anal canal in the midline posteriorly...

     of anal fistula
  • The Ileo-anal pouch
    Ileo-anal pouch
    The ileal pouch-anal anastomosis , also known as an ileo-anal pouch, restorative proctocolectomy, ileal-anal pullthrough, or sometimes referred to as a j-pouch, s-pouch, w-pouch or an internal pouch, is an internal reservoir; usually situated where the rectum would normally be...

    , a replacement rectum, was developed at St Mark’s in the 1970s by Alan Parks
  • St. Mark's polyposis registry, established in 1924, is the oldest in the world and scientists funded by the Imperial Cancer Research Fund, based at St Mark's, played an important role in identifying the APC
    APC (gene)
    Adenomatous polyposis coli also known as deleted in polyposis 2.5 is a protein that in humans is encoded by the APC gene. Mutations in the APC gene may result in colorectal cancer....

     gene responsible for causing Familial adenomatous polyposis
    Familial adenomatous polyposis
    Familial adenomatous polyposis is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs when not treated....

    .
  • Recent Academic Publications]

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
x
OK