Spinal Muscular Atrophy Type 2 (also known as "spinal muscular atrophy type II") is an autosomal recessive disease and is a form of spinal muscular atrophy

Spinal muscular atrophy

Spinal Muscular Atrophy is a neuromuscular disease characterized by degeneration of motor neurons, resulting in progressive muscular atrophy and weakness. The clinical spectrum of SMA ranges from early infant death to normal adult life with only mild weakness...

 (SMA).

Symptoms

Children with spinal muscular atrophy type 2 manifest less severe weakness than children with Werdnig-Hoffman disease. Symptoms are usually noticed later in life, usually between the age of 6 to 18 months. The clinical features are similar to those found in children with Type 1; in fact, there are many children for whom the characterization of Type 1 (Werdnig-Hoffman) or Type 2 SMA becomes a "best guess". Children with Type 2 SMA usually achieve the ability to sit independently, however, they almost never achieve the ability to walk or stand without support.

Prognosis

Some children with SMA Type 2 have a relatively static course and remain free of life threatening complications such as pneumonia. Other children, have progressive weakness of their swallowing and respiratory muscles. Many youngsters with SMA Type 2 develop curvature of the spine (Kyphoscoliosis) and other orthopedic problems. Skillful management by a team of physical therapists and orthopedic surgeons is usually needed to manage these problems.

See also

• Motor neurone disease
  Motor neurone disease
  The motor neurone diseases are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body. They are generally progressive in nature, and can cause...
  
  
• Spinal Muscular Atrophy
  Spinal muscular atrophy
  Spinal Muscular Atrophy is a neuromuscular disease characterized by degeneration of motor neurons, resulting in progressive muscular atrophy and weakness. The clinical spectrum of SMA ranges from early infant death to normal adult life with only mild weakness...
  
  
• Kugelberg-Welander disease
• Werdnig-Hoffman disease
• ladyjenivie
• http://www.blogtv.com/people/ladyjenivie

Source

• Fight SMA Spinal Muscular Atrophy Guidebook