South Carolina Highway 296 is an east-west route coursing through central Greenville and Spartanburg counties.

Route description

The west terminus of SC 296 is at a junction with SC 14

South Carolina Highway 14

Highway 14 is a state highway located in the U.S. state of South Carolina. It begins at an intersection with U.S. 76 in Laurens, South Carolina, and ends at I-26 near Landrum.-History:...

 in west-central Greenville County and proceeds in a generally east-northeast direction. Shortly after the junction, the route merges with SC 146

South Carolina Highway 146

South Carolina Highway 146 is a thirty-three-mile South Carolina state highway running through Central Greenville County and south-western Spartanburg County.-Route description:...

, but soon separates from SC 146 a short distance afterward. South Carolina Highway 296 then crosses into Spartanburg County as it traverses the Enoree River

Enoree River

The Enoree River is a tributary of the Broad River, 85 mi long, in northwestern South Carolina in the United States . Via the Broad and Congaree Rivers, it is part of the watershed of the Santee River, which flows to the Atlantic Ocean ....

, and then intersects with SC 101

South Carolina Highway 101

South Carolina Highway 101 is a state route in Greenville, Spartanburg, and Laurens counties. Its northern terminus is at a junction with SC 11 near Landrum, SC, and its southern terminus is at a junction with US 76 in Hickory Tavern, SC.-Route description:The north terminus of South Carolina...

 before passing through Reidville. Then, SC 296 intersects with SC 290

South Carolina Highway 290

South Carolina Highway 290 is a South Carolina State Highway that courses through central Greenville and Spartanburg Counties.-Route description:...

 and SC 417

South Carolina Highway 417

South Carolina Highway 417 is a numbered highway in Central Greenville and Spartanburg counties.-Route description:SC 417's western terminus is at junction with US 276 in Mauldin, SC and near the junctions of I-385 and I-185...

 before intersecting with Interstate 26

Interstate 26

Interstate 26 is a nominally east–west main route of the Interstate Highway System in the Southeastern United States. I-26 runs from the junction of U.S. Route 11W and U.S. Route 23 in Kingsport, Tennessee, generally southeastward to U.S. Route 17 in Charleston, South Carolina...

 at exit 22 just outside the Spartanburg city limits. Within the city, SC 296 junctions with US 29 and US 221, and finally reaches its eastern terminus with US 176 and SC 9.

Major intersections

County	Location	Mile	Destinations	Notes
Greenville	Five Forks	0.0		Western terminus
		1.7		Start SC 146 concurrency
		2.4		End SC 146 concurrency
Spartanburg	Sugar Tit	7.6
	Poplar Springs	13.0
		14.2		Eastern terminus of SC 417
	Spartanburg Spartanburg, South Carolina thgSpartanburg is the largest city in and the county seat of Spartanburg County, South Carolina, United States. It is the second-largest city of the three primary cities in the Upstate region of South Carolina, and is located northwest of Columbia, west of Charlotte, and about northeast of...	18.3		Exit 22 (I-26)
		18.5		Northern terminus of SC 215
		18.5		Start SC 295 concurrency
		19.4		End SC 295 concurrency
		22.5
		22.9
		23.5		Eastern terminus