Soai reaction
Encyclopedia
Soai reaction is alkylation
of pyrimidine-5-carbaldehyde by diisopropylzinc
. The product pyrimidyl alcohol acts as an autocatalyst, and with low enantiomeric excess yield product with very high enantiomeric excess.
The Japanese chemist Kenso Soai (1950–) discovered the reaction in 1995.
Alkylation
Alkylation is the transfer of an alkyl group from one molecule to another. The alkyl group may be transferred as an alkyl carbocation, a free radical, a carbanion or a carbene . Alkylating agents are widely used in chemistry because the alkyl group is probably the most common group encountered in...
of pyrimidine-5-carbaldehyde by diisopropylzinc
Diisopropylzinc
Diisopropylzinc is an organozinc compound with the chemical formulaZnC6H14....
. The product pyrimidyl alcohol acts as an autocatalyst, and with low enantiomeric excess yield product with very high enantiomeric excess.
The Japanese chemist Kenso Soai (1950–) discovered the reaction in 1995.