The Simian Varicella Virus or SVV infects primates and shares clinical, pathological, immunological, and virological features with varicella-zoster virus infection of humans. Monkeys that had been inoculated intratracheally with SVV developed diffuse varicella 10 to 12 days later. Monkeys that were caged with each of the intratracheally infected monkeys developed a mild rash 2 weeks later, hence providing evidence of airborne transmission.