"Save Me is the eighth episode of the first season of the ABC

American Broadcasting Company

The American Broadcasting Company is an American commercial broadcasting television network. Created in 1943 from the former NBC Blue radio network, ABC is owned by The Walt Disney Company and is part of Disney-ABC Television Group. Its first broadcast on television was in 1948...

 series, Grey's Anatomy

Grey's Anatomy

Grey's Anatomy is an American medical drama television series created by Shonda Rhimes. The series premiered on March 27, 2005 on ABC; since then, seven seasons have aired. The series follows the lives of interns, residents and their mentors in the fictional Seattle Grace Mercy West Hospital in...

. The episode was written by Mimi Schmir

Mimi Schmir

Mimi Schmir is an American television producer and screenwriter. Her most notable work has been for the medical drama Grey's Anatomy, for which she has served as producer, supervising producer and writer for over thirty episodes, and the legal drama Shark, for which she has served as writer and...

 and was directed by Sara Pia Anderson

Sara Pia Anderson

Sarah Pia Anderson is a television director. After a career in the theatre, her early television work included Prime Suspect 4: Inner Circles , starring Helen Mirren...

. It originally aired on Sunday May 15, 2005, running for 42:48 min.

Starring

• Ellen Pompeo
  Ellen Pompeo
  Ellen Kathleen Pompeo is an American actress, known for playing the title role of Meredith Grey on the ABC medical drama Grey's Anatomy.-Early life:...
  
   as Dr. Meredith Grey.
• Sandra Oh
  Sandra Oh
  Sandra Oh is a Canadian actress. She is best known for the role of Dr. Cristina Yang on ABC's Grey's Anatomy, for which she has won a Golden Globe and Screen Actors Guild award. She also played notable roles in the feature films Under the Tuscan Sun and Sideways, and had a supporting role on the...
  
   as Dr. Cristina Yang.
• Katherine Heigl
  Katherine Heigl
  Katherine Marie Heigl is an American actress and producer. She is possibly best known for her role as Dr. Izzie Stevens on ABC's Grey's Anatomy from 2005 to 2010, for which she won a Primetime Emmy Award for Outstanding Supporting Actress – Drama Series in 2007...
  
   as Dr. Izzie Stevens.
• Justin Chambers
  Justin Chambers
  Justin W. Chambers is an American actor and former Calvin Klein male fashion model. As of 2005, he is starring in the ABC drama series Grey's Anatomy as Dr. Alex Karev....
  
   as Dr. Alex Karev.
• T.R. Knight as Dr. George O'Malley.
• Chandra Wilson
  Chandra Wilson
  Chandra Danette Wilson is an American actress and director, best known as Dr. Miranda Bailey in the ABC television drama, Grey's Anatomy.-Early life:...
  
   as Dr. Miranda Bailey.
• James Pickens, Jr.
  James Pickens, Jr.
  James Pickens, Jr. is an American actor. He is best known for his starring role as Dr. Richard Webber on the ABC drama television series Grey's Anatomy, and for his supporting role as Deputy Director Alvin Kersh on later seasons of the Fox Network science fiction series The X-Files.- Early life...
  
   as Dr. Richard Webber.
• Isaiah Washington
  Isaiah Washington
  Isaiah Washington IV is an American actor. A veteran of several Spike Lee films, Washington is best known for his role as Dr. Preston Burke on the ABC medical drama Grey's Anatomy from 2005 to 2007.-Personal life:...
  
   as Dr. Preston Burke.
• Patrick Dempsey
  Patrick Dempsey
  Patrick Galen Dempsey is an American actor, known for his role as neurosurgeon Dr. Derek Shepherd on the medical drama Grey's Anatomy. Prior to Grey's Anatomy he made several television appearances and was nominated for an Emmy Award...
  
   as Dr. Derek Shepherd.

Episode Recap

Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient (of Jewish descent) whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.

Music

• "No Illusions" - 78 Saab
• "I Love the Rain the Most" - Joe Purdy
  Joe Purdy
  Joe Purdy is an American folk singer-songwriter who has recorded and released ten albums in eight years.- The band :Joe Purdy's band members have included: Chris Seefried, Brian Wright, Willy C. Golden, , and .- Career :...
  
  
• "Rapture" - Laura Veirs
  Laura Veirs
  Laura Pauline Veirs is an American singer-songwriter.Veirs was raised in Colorado, studied geology and Mandarin Chinese at Carleton College, worked as a translator for a geological expedition in China, and now lives in Portland, Oregon.While growing up, she heard folk-country, classical, and pop...
  
  
• "Feels Like" - Masha Qrella
• "David" - Nellie McKay
  Nellie McKay
  Nellie McKay , is an American singer-songwriter, actor, and former stand-up comedienne, noted for her critically acclaimed albums, and for her Broadway debut in The Threepenny Opera , for which she won a Theatre World Award...
  
  
• "Fix You Up" - Tegan and Sara
  Tegan and Sara
  Tegan and Sara are a Canadian indie band composed of identical twin sisters Tegan Rain Quin and Sara Keirsten Quin . Both Tegan and Sara play guitar and keyboard and write songs.-History:...
  
  

Title Reference

The episode's title refers to a song by Jem (singer)

Jem (singer)

Jemma Griffiths , better known as Jem, is a Welsh singer-songwriter. Her debut album, Finally Woken, includes elements of rock, new wave-styled electronica and trip-hop...

, which was used in an earlier episode, If Tomorrow Never Comes (Grey's Anatomy)

If Tomorrow Never Comes (Grey's Anatomy)

"If Tomorrow Never Comes" is the sixth episode of the first season of the ABC series, Grey's Anatomy. The episode was written by Krista Vernoff and was directed by Scott Brazil. It was originally broadcast on Sunday May 1, 2005, running for 42:55 min....

.