Saralasin
Encyclopedia
Saralasin is a competitive inhibitor of angiotensin II. It is an angiotensin II analogue, containing sarcosine
-1 and alanine
-8, hence the name (sarcosine, alanine, angiotensin).
Sarcosine
Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-N-methyl transferase generates sarcosine from glycine. Sarcosine is a natural amino acid found in...
-1 and alanine
Alanine
Alanine is an α-amino acid with the chemical formula CH3CHCOOH. The L-isomer is one of the 20 amino acids encoded by the genetic code. Its codons are GCU, GCC, GCA, and GCG. It is classified as a nonpolar amino acid...
-8, hence the name (sarcosine, alanine, angiotensin).