Sana-Kan is one of the main characters from BLAME!

Blame!

, pronounced "blam", is a ten-volume 1998 cyberpunk manga by Tsutomu Nihei published by Kodansha. A six part original net animation was produced in 2003, with a seventh episode included on the DVD release.- Plot :...

, a manga

Manga

Manga is the Japanese word for "comics" and consists of comics and print cartoons . In the West, the term "manga" has been appropriated to refer specifically to comics created in Japan, or by Japanese authors, in the Japanese language and conforming to the style developed in Japan in the late 19th...

 by Tsutomu Nihei

Tsutomu Nihei

is a Japanese manga artist. His cyberpunk-influenced artwork has gained a strong cult following. He has a relatively large community of fans in Germany where his manga Blame!, NOiSE and Biomega were published by Ehapa. Blame! was also published in France and Spain by Glénat, in the US by Tokyopop...

.

She is first seen as a short, young girl with black hair who finds Killy

Killy (Blame!)

-Description:Killy is a fictional character from the manga series Blame!, by Tsutomu Nihei. He is tasked by an unknown agency with finding a human in the 32-AU radius Megastructure who still possesses the Net Terminal Gene, a genetic marker necessary for safe access to the Netsphere, from which...

 and Cibo

Cibo

Cibo is a main character in the manga BLAME! by Tsutomu Nihei. She is the head scientist of the Bio-Electric Corporation in the Capitol and joins Killy on his quest for the Net Terminal Gene....

 in a tunnel after they pierce the impenetrable Megastructure

Megastructure

A megastructure is a very large manmade object, though the limits of precisely how large this is vary considerably. Some apply the term to any especially large or tall building....

 layer with the GBE.
Killy later discovers her true nature and she reveals herself as a level 6 Safeguard with a GBE similar to Killy's.

At first, Sana-Kan behaves like any Safeguard intent on annihilating all humans without the Net Terminal Gene. This changes however, when she becomes a representative of the Governing Agency with the task of retrieving Cibo, who at that time becomes the illegal level 9 Safeguard unit. At this point, she adapts a more protective role.

Sana-Kan's physical body was destroyed twice in the line of duty; First in order to destroy the Toha Heavy Industries' Central AI and for the second time while protecting Cibo from Silicon Creatures. She finally dies when she sacrifices herself in order to save Killy and the globe that Cibo carried from an Exterminator.

Sana-Kan has been the second "mother" of the child with the net terminal genes, along with Cibo, who was carrying the globe with the embryo.
There is, however, a popular theory pieced together from fan forums that Susono Musubi from NOiSE is somehow closely associated with Sana-Kan.

Susono Musubi was a human during NetSphere's Beta phase, she was then captured and modified into a Silicon Life-form.
The transformation was issued by the NetSphere officials (later the powerless Governing Body) thus the technologies were
complete and superior in comparison to the Silicon creatures' knowledge from hacking the NetSphere archives. This is
evident in both appearance and functionality. NetSphere body modifications enable the manifestation to maintain the
outer appearance of human and self-repairing capabilities while illegitimate Silicon creatures do not.

Susono was one of the first original Safe Guards deployed by the NetSphere to stop hacking attempts and annihilate
illegal Silicon Creatures made from stolen NetSphere technologies. The NetSphere was originally designed to be a
dream-realisation machine for the good of mankind, as it grants the registered End-User access to God-like privileges,
but it was perverted by the Society Elites who thirst for more power and longevity. Later overwhelmed by hacking attempts
from rebel groups, activists and profit-oriented criminals, the NetSphere crashed and went into Self-protective overdrive,
that rejected its terminal authentication and stopped issueing new End-user licenses altogether.

Susono's profile withheld in the NetSphere library became the Template that materialised into Sana-Kan, a sleeper
type Safe Guard placed close to Toha Heavy Industries in order to sabotage the truce treaty Toha signed with the NetSphere.
Since Susono was a Safe Guard before the NetSphere-crash, her digitized data was not catergorized under normal
Safe Guard groups. This is why Sana-Kan is the only Safe Guard within the NetSphere that the Governing Body had the administrative
power to overwrite her old orders and assign her the new mission to protect Cibo. This could explain the sudden shift in Sana-kan's stance.

The Template theory also made sense of Cibo and Sana-Kan's NetSphere accessible embryo. Susono's DNA data from the
NetSphere Archive is the only profile with an End-User license, combined with access privileges provided by Lv9 Safe Guard Cibo to
by-pass NetSphere firewalls, their embryo could potentially connect to the NetSphere and order The City to
stop expanding and reset the NetSphere Alarm Status.