Sabin Vaccine Institute
Encyclopedia
The Sabin Vaccine Institute ("Sabin") is a non-profit, 501(c)(3) organization dedicated to reducing needless human
suffering from vaccine preventable and neglected tropical diseases through prevention and treatment. Sabin advocates for the control of infectious diseases such as HPV, pneumococcal disease
Pneumococcal infection
- Pathogenesis :S. pneumoniae is normally found in the nasopharynx of 5-10% of healthy adults, and 20-40% of healthy children. It can be found in higher amounts in certain environments, especially those where people are spending a great deal of time in close proximity to each other...

, pertussis
Pertussis
Pertussis, also known as whooping cough , is a highly contagious bacterial disease caused by Bordetella pertussis. Symptoms are initially mild, and then develop into severe coughing fits, which produce the namesake high-pitched "whoop" sound in infected babies and children when they inhale air...

, rotavirus
Rotavirus
Rotavirus is the most common cause of severe diarrhoea among infants and young children, and is one of several viruses that cause infections often called stomach flu, despite having no relation to influenza. It is a genus of double-stranded RNA virus in the family Reoviridae. By the age of five,...

, rubella
Rubella
Rubella, commonly known as German measles, is a disease caused by the rubella virus. The name "rubella" is derived from the Latin, meaning little red. Rubella is also known as German measles because the disease was first described by German physicians in the mid-eighteenth century. This disease is...

, and typhoid and neglected tropical diseases
Neglected Diseases
The neglected diseases are a group of tropical infections which are especially endemic in low-income populations in developing regions of Africa, Asia, and the Americas. Different organizations define the set of diseases differently...

 (NTDs) including human hookworm infection
Hookworm
The hookworm is a parasitic nematode that lives in the small intestine of its host, which may be a mammal such as a dog, cat, or human. Two species of hookworms commonly infect humans, Ancylostoma duodenale and Necator americanus. A. duodenale predominates in the Middle East, North Africa, India...

, ascariasis
Ascariasis
Ascariasis is a human disease caused by the parasitic roundworm Ascaris lumbricoides. Perhaps as many as one quarter of the world's people are infected, with rates of 45% in Latin America and 95% in parts of Africa. Ascariasis is particularly prevalent in tropical regions and in areas of poor...

, trichuriasis
Trichuriasis
Trichuriasis is a parasitic infection primarily in the tissue of the cecum, appendix, colon and rectum that is caused by Trichuris trichiura , an intestinal parasitic nematode .-Agent :...

, schistosomiasis
Schistosomiasis
Schistosomiasis is a parasitic disease caused by several species of trematodes , a parasitic worm of the genus Schistosoma. Snails often act as an intermediary agent for the infectious diseases until a new human host is found...

, onchocerciasis
Onchocerciasis
Onchocerciasis , also known as river blindness and Robles' disease, is a parasitic disease caused by infection by Onchocerca volvulus, a nematode . Onchocerciasis is the world's second-leading infectious cause of blindness. It is not the nematode, but its endosymbiont, Wolbachia pipientis, that...

, lymphatic filariasis (elephantiasis), and trachoma
Trachoma
Trachoma is an infectious disease causing a characteristic roughening of the inner surface of the eyelids. Also called granular conjunctivitis and Egyptian ophthalmia, it is the leading cause of infectious blindness in the world...

.

History

The Sabin Vaccine Institute was founded in 1993 by Dr. H.R. Shepherd, Mrs. Heloisa Sabin, Dr. Robert M. Chanock
Robert M. Chanock
Robert Merritt Chanock was an American pediatrician and virologist who made major contributions to the prevention and treatment of childhood respiratory infections in more than 50 years spent at the National Institute of Allergy and Infectious Diseases.Chanock was born July 8, 1924 in Chicago. His...

, and Dr. Philip K. Russell and named in honor of one of medicine’s most pre-eminent scientific figures, Dr. Albert B. Sabin
Albert Sabin
Albert Bruce Sabin was an American medical researcher best known for having developed an oral polio vaccine.-Life:...

, best known for developing the oral live virus polio vaccine
Polio vaccine
Two polio vaccines are used throughout the world to combat poliomyelitis . The first was developed by Jonas Salk and first tested in 1952. Announced to the world by Salk on April 12, 1955, it consists of an injected dose of inactivated poliovirus. An oral vaccine was developed by Albert Sabin...

. The Institute continues Dr. Sabin’s vision by providing greater access to vaccines and essential treatments for hundreds of millions of people stuck in a cycle of pain, poverty and despair through its three main programs – Sabin Vaccine Development, the Global Network for Neglected Tropical Diseases
Global Network for Neglected Tropical Diseases
The Global Network for Neglected Tropical Diseases is an advocacy initiative of the Sabin Vaccine Institute dedicated to raising the awareness, political will, and funding necessary to control and eliminate the most common Neglected Tropical Diseases --a group of disabling, disfiguring, and deadly...

, and Vaccine Advocacy and Education.

Programs

Through three distinct yet complementary programs, the Institute continues Dr. Sabin’s lifelong efforts to develop preventive measures for diseases that place heavy burdens on the world’s poorest countries:
  • Global Network for Neglected Tropical Diseases
    Global Network for Neglected Tropical Diseases
    The Global Network for Neglected Tropical Diseases is an advocacy initiative of the Sabin Vaccine Institute dedicated to raising the awareness, political will, and funding necessary to control and eliminate the most common Neglected Tropical Diseases --a group of disabling, disfiguring, and deadly...

    ,
    an advocacy and resource mobilization program dedicated to eliminating the most common disabling, disfiguring and deadly neglected tropical diseases (NTDs), was launched at the 2006 Clinton Global Initiative. Through a network of partnering international agencies, scientists and advocates, the Global Network aims to raise the awareness, political will, and funding necessary to control and eliminate the seven most common NTDs that blind, disable, disfigure and stigmatize 1.4 billion of the world’s poorest people.

  • Sabin Vaccine Development aims to develop sustainable and cost-effective vaccines to prevent several parasitic and neglected tropical diseases, including hookworm, schistosomiasis, and malaria. Through a collaborative product development partnership with The George Washington University and other international academic institutions and organizations, the program’s 10 year research and development experience has produced a well-rounded, low-cost model that serves as a blue print for vaccine research and development and ongoing efforts to fight public health threats that adversely impact more than one billion people worldwide.

  • Vaccine Advocacy and Education works with leading health experts and organizations to promote global awareness of infectious diseases and the immunizations needed to combat their debilitating effects. The program focuses on providing decision-makers with the information and resources needed to introduce and sustainably fund safe and effective immunization programs against pneumococcal disease, neglected tropical diseases (NTDs), rotavirus, human papillomavirus (HPV), rubella, and other infectious diseases. Initiatives of the program include the Pneumococcal Awareness Council of Experts (PACE), the Sustainable Immunization Financing(SIF) program, and the Coalition against Typhoid (CaT) :

  • The Pneumococcal Awareness Council of Experts (PACE)
    Pneumococcal Awareness Council of Experts
    ‎The Pneumococcal Awareness Council of Experts is a project of the Sabin Vaccine Institute and is composed of global experts in infectious diseases and vaccines. Established in December 2006, The Council seeks to raise awareness among policymakers and aims to secure global commitments to prevent...

    was founded in 2006 to raise awareness of pneumococcal disease and advocate for its prevention through the use of vaccines.http://www.sabin.org/PACE

  • The Sustainable Immunization Financing (SIF) program aims to assist governments in building internal capacity to increase their share of funding for vaccines. Active in 15 developing countries throughout Africa and Asia, SIF experts and staff work to ensure that key decision-makers have the information and resources they need to introduce and sustainably fund safe and effective immunization programs.

  • The Coalition against Typhoid
    Coalition against Typhoid
    The Coalition against Typhoid is a global forum of health and immunization experts working to save lives and reduce suffering by accelerating the delivery of typhoid vaccines to populations that need them most....

     (CaT)
    http://www.sabin.org/advocacy-education/coalition-against-typhoid is a global forum of health and immunization experts working to expedite and sustain evidence-informed decisions at the global, regional and country levels regarding the use of typhoid vaccination to prevent childhood enteric fever.

The Albert B. Sabin Gold Medal

The Albert B. Sabin Gold Medal is awarded annually by the Sabin Vaccine Institute in recognition of outstanding achievement in the field of vaccinology. The award commemorates the pioneering work in this field by the late Dr. Albert B. Sabin, discoverer of the oral polio vaccine
Polio vaccine
Two polio vaccines are used throughout the world to combat poliomyelitis . The first was developed by Jonas Salk and first tested in 1952. Announced to the world by Salk on April 12, 1955, it consists of an injected dose of inactivated poliovirus. An oral vaccine was developed by Albert Sabin...

.
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