SUV39H1
Encyclopedia
Histone-lysine N-methyltransferase SUV39H1 is an enzyme
that in humans is encoded by the SUV39H1 gene
.
with HDAC9
, HDAC1
, Histone deacetylase 2
, Retinoblastoma protein
, CBX5
, HDAC3
, DNMT3A
, MBD1
, RUNX1
, SBF1
and CBX1
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the SUV39H1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
SUV39H1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with HDAC9
HDAC9
Histone deacetylase 9 is an enzyme that in humans is encoded by the HDAC9 gene.-Interactions:HDAC9 has been shown to interact with SIN3A, Nuclear receptor co-repressor 1, CBX5, HDAC3, Myocyte-specific enhancer factor 2A and SUV39H1....
, HDAC1
HDAC1
Histone deacetylase 1 is an enzyme that in humans is encoded by the HDAC1 gene.-Interactions:HDAC1 has been shown to interact with RAD9A, DNMT3L, MTA1, FKBP3, CDC20, CDH1, Host cell factor C1, BUB3, Nuclear receptor co-repressor 2, IKZF1, Prohibitin, EVI1, DDX5, DNMT3A, Mothers against...
, Histone deacetylase 2
Histone deacetylase 2
Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene.-Interactions:Histone deacetylase 2 has been shown to interact with CHD3, MTA1, FKBP3, CHD4, RCOR1, Retinoblastoma protein, CDC20, RBBP4, CDH1, EED, GTF2I, Host cell factor C1, PHF21A, BUB3, MXD1, HDAC10, RELA, Sp3...
, Retinoblastoma protein
Retinoblastoma protein
The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in the majority types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide...
, CBX5
CBX5 (gene)
Chromobox protein homolog 5 is a protein that in humans is encoded by the CBX5 gene.-Interactions:CBX5 has been shown to interact with HDAC9, Ku70, MIS12, Lamin B receptor, MBD1, TAF4, Histone deacetylase 5, TRIM28, HDAC4, CBX3, SMARCA4, DNMT3B, CHAF1A, CBX1 and SUV39H1....
, HDAC3
HDAC3
Histone deacetylase 3 is an enzyme that in humans is encoded by the HDAC3 gene.-Interactions:HDAC3 has been shown to interact with HDAC9, HDAC7A, Retinoblastoma protein, RBBP4, Testicular receptor 2, MAP3K7IP2, Peroxisome proliferator-activated receptor delta, GTF2I, Histone deacetylase 5, RELA,...
, DNMT3A
DNMT3A
DNA -methyltransferase 3A is an enzyme that in humans is encoded by the DNMT3A gene.-Interactions:DNMT3A has been shown to interact with ZNF238, HDAC1, Myc, Protein inhibitor of activated STAT2, DNMT1, DNMT3B, PIAS1, UBE2I and SUV39H1....
, MBD1
MBD1
Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the MBD1 gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequences, and appears to mediate repression of gene expression...
, RUNX1
RUNX1
Runt-related transcription factor 1 also known as acute myeloid leukemia 1 protein or core-binding factor subunit alpha-2 is a protein that in humans is encoded by the RUNX1 gene....
, SBF1
SBF1
Myotubularin-related protein 5 is a protein that in humans is encoded by the SBF1 gene.-Interactions:SBF1 has been shown to interact with MTMR2 and SUV39H1.-Further reading:...
and CBX1
CBX1
Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene.-Interactions:CBX1 has been shown to interact with C11orf30, CBX5, CBX3 and SUV39H1.-Further reading:...
.