SR-48692 is a drug which acts as a selective, non-peptide antagonist at the neurotensin

Neurotensin

Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction with the dopaminergic system...

 receptor

Receptor (biochemistry)

In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...

 NTS₁

Neurotensin receptor 1

Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene.-Further reading:...

, and was the first non-peptide antagonist developed for this receptor. It is used in scientific research to explore the interaction between neurotensin and other neurotransmitters in the brain, and produces anxiolytic

Anxiolytic

An anxiolytic is a drug used for the treatment of anxiety, and its related psychological and physical symptoms...

, anti-addictive and memory-impairing effects in animal studies.