SLC14A1
Encyclopedia
Urea transporter, erythrocyte is a protein
that in humans is encoded by the SLC14A1 gene
.
(UTB) that is expressed in erythrocytes and kidney
. SLC14A2
and SLC14A1 constitute solute carrier family
14. UTB proteins constitute the Kidd antigen system
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the SLC14A1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
The SLC14A1 codes for a urea transporterUrea transporter
An urea transporter is a membrane transport protein, transporting urea. Humans and other mammals have two types of urea transport proteins, UT-A and UT-B. The UT-A proteins are important for renal urea handling and are produced by alternative splicing of the SLC14A2 gene...
(UTB) that is expressed in erythrocytes and kidney
Kidney
The kidneys, organs with several functions, serve essential regulatory roles in most animals, including vertebrates and some invertebrates. They are essential in the urinary system and also serve homeostatic functions such as the regulation of electrolytes, maintenance of acid–base balance, and...
. SLC14A2
SLC14A2
Urea transporter, kidney also known as urea transporter 2 or solute carrier family 14 member 2 is a protein that in humans is encoded by the SLC14A2 gene.- Function :...
and SLC14A1 constitute solute carrier family
Solute carrier family
The solute carrier group of membrane transport proteins include over 300 members organized into 51 families. The SLC gene nomenclature system was originally proposed by the Human Genome Organization and is the basis for the official HUGO names of the genes that encode these transporters...
14. UTB proteins constitute the Kidd antigen system
Kidd antigen system
The Kidd antigen system is present on the membranes of red blood cells and the kidney and helps determine a person's blood type. The Jk antigen is found on a protein responsible for urea transport in the red blood cells and the kidney. The gene encoding this protein is found on chromosome 18....
.