SIAH2
Encyclopedia
E3 ubiquitin-protein ligase SIAH2 is an enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that in humans is encoded by the SIAH2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Interactions

SIAH2 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with PEG10
PEG10
Retrotransposon-derived protein PEG10 is a protein that in humans is encoded by the PEG10 gene.-Interactions:PEG10 has been shown to interact with SIAH2 and SIAH1.-Further reading:...

, Synaptophysin
Synaptophysin
Synaptophysin also known as the major synaptic vesicle protein p38 is a protein that in humans is encoded by the SYP gene.-Genomics:...

, PEG3
PEG3
Paternally-expressed gene 3 protein is a protein that in humans is encoded by the PEG3 gene.-Interactions:PEG3 has been shown to interact with SIAH2 and SIAH1.-Further reading:...

 and VAV1
VAV1
Proto-oncogene vav is a protein that in humans is encoded by the VAV1 gene.-Interactions:VAV1 has been shown to interact with Ku70, PLCG1, Lymphocyte cytosolic protein 2, Janus kinase 2, SIAH2, S100B, Abl gene, ARHGDIB, SHB, PIK3R1, PRKCQ, Grb2, MAPK1, Syk, Linker of activated T cells, Cbl gene and...

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Further reading

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