SH2D1A
Encyclopedia
SH2 domain-containing protein 1A is a protein
that in humans is encoded by the SH2D1A gene
.
It is associated with X-linked lymphoproliferative disease
.
with FYN
, SLAMF1
, CD84
, LY9
and DOK1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the SH2D1A gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
It is associated with X-linked lymphoproliferative disease
X-linked lymphoproliferative disease
X-linked lymphoproliferative disease is a lymphoproliferative disorder.-XLP1:There is a mutation on the X-chromosome that has been found to be associated with a T- and NK-cell lymphoproliferative disorder. The mutation is on the long arm of the chromosome, at position 25, which is denoted as Xq25...
.
Interactions
SH2D1A has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with FYN
FYN
Proto-oncogene tyrosine-protein kinase Fyn is an enzyme that in humans is encoded by the FYN gene.This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth...
, SLAMF1
SLAMF1
Signaling lymphocytic activation molecule is a protein that in humans is encoded by the SLAMF1 gene.SLAMF1 has also recently has been designated CD150 .-Interactions:...
, CD84
CD84
CD84 is a human protein encoded by the gene....
, LY9
LY9
T-lymphocyte surface antigen Ly-9 is a protein that in humans is encoded by the LY9 gene. LY9 has also recently been designated CD229 ....
and DOK1
DOK1
Docking protein 1 is a protein that in humans is encoded by the DOK1 gene.-Interactions:DOK1 has been shown to interact with RET proto-oncogene, SH2D1A, LYN, RAS p21 protein activator 1, INPP5D, CD117, SHC1, Abl gene and TEC.-Further reading:...
.