New England Route 28 was a 180 miles (289.7 km) north–south New England Interstate Route from Buzzards Bay, Massachusetts

Buzzards Bay, Massachusetts

Buzzards Bay is a census-designated place in the town of Bourne in Barnstable County, Massachusetts. The population was 3,549 at the 2000 census.-Geography:Buzzards Bay is located at...

 (at NE-3) to Ossipee, New Hampshire

Ossipee, New Hampshire

Ossipee is a town in Carroll County, New Hampshire, United States. The population was 4,345 at the 2010 census. It is the county seat of Carroll County...

 (at NE-16) via Boston

Boston

Boston is the capital of and largest city in Massachusetts, and is one of the oldest cities in the United States. The largest city in New England, Boston is regarded as the unofficial "Capital of New England" for its economic and cultural impact on the entire New England region. The city proper had...

 and Manchester, New Hampshire

Manchester, New Hampshire

Manchester is the largest city in the U.S. state of New Hampshire, the tenth largest city in New England, and the largest city in northern New England, an area comprising the states of Maine, New Hampshire, and Vermont. It is in Hillsborough County along the banks of the Merrimack River, which...

. The portion in Massachusetts has since been extended east into Cape Cod

Cape Cod

Cape Cod, often referred to locally as simply the Cape, is a cape in the easternmost portion of the state of Massachusetts, in the Northeastern United States...

 (along the original alignment of NE-3) and currently ends at the Orleans Rotary in the town of Orleans

Orleans, Massachusetts

Orleans is a town in Barnstable County, Massachusetts, United States. Barnstable County is coextensive with Cape Cod. The population was 5,890 at the 2010 census....

 with US 6 and Route 6A

Route 6A (Massachusetts)

Route 6A is the name for parts of former U.S. Route 6 on Cape Cod. Most of "6A", as the locals call it, is also known as the Old King's Highway...

.

The 1922 plan originally had NE-28 ending in Bethel, Maine

Bethel, Maine

Bethel is a town in Oxford County, Maine, United States. The population was 2,411 at the 2000 census. It includes the villages of West Bethel and South Bethel...

. North of Ossipee, the original route followed current New Hampshire Route 16

New Hampshire Route 16

New Hampshire Route 16 is a long north–south highway in the U.S. state of New Hampshire. Much of its length is close to the border with Maine. NH 16 is the main route from the Seacoast region north to the Lakes Region and the White Mountains. The section from Portsmouth to Milton is a...

 (NE-16) to Conway

Conway, New Hampshire

Conway is a town, the largest in Carroll County, New Hampshire, United States. The population was 10,115 at the 2010 census. Parts of the White Mountain National Forest are in the west and north. Cathedral Ledge and Echo Lake State Park are in the west...

, then U.S. Route 302

U.S. Route 302

U.S. Route 302 is a spur of U.S. Route 2. It currently runs 171 miles north from Portland, Maine, at U.S. Route 1, to Montpelier, Vermont, at US 2...

 (NE-18) to Fryeburg, Maine, and then State Route 5 to Bethel

Bethel, Maine

Bethel is a town in Oxford County, Maine, United States. The population was 2,411 at the 2000 census. It includes the villages of West Bethel and South Bethel...

. There have been some minor realignments over the years, particularly in urban areas, but the original route remains mostly intact. NE-28 parallels Route 25

Route 25 (Massachusetts)

Route 25 is a numbered state highway located in Plymouth County and Barnstable County, Massachusetts, United States. The route is a nominally east–west freeway for its entire length, and less commonly known as the Blue Star Memorial Highway. An eastward continuation of Interstate 495, Route 25...

/I-495 from Bourne, Massachusetts

Bourne, Massachusetts

Bourne is a town in Barnstable County, Massachusetts, United States. The population was 18,721 at the 2000 census.For geographic and demographic information on specific parts of the town of Bourne, please see the articles on Bourne , Buzzards Bay, Monument Beach, Pocasset, Sagamore, and Sagamore...

 to Bridgewater

Bridgewater, Massachusetts

For geographic and demographic information on the census-designated place Bridgewater, please see the article Bridgewater , Massachusetts.The Town of Bridgewater is a city in Plymouth County, Massachusetts, United States, 28 miles south of Boston. At the 2000 Census, the population was 25,185...

; Route 24

Route 24 (Massachusetts)

Route 24 is a freeway south of I-93 in southeastern Massachusetts, linking Fall River with the Boston metropolitan area. It begins in the south in Fall River at the border with Tiverton, Rhode Island where it connects with Rhode Island Route 24, and runs north to an interchange with Interstate...

 from Bridgewater to Quincy

Quincy, Massachusetts

Quincy is a city in Norfolk County, Massachusetts, United States. Its nicknames are "City of Presidents", "City of Legends", and "Birthplace of the American Dream". As a major part of Metropolitan Boston, Quincy is a member of Boston's Inner Core Committee for the Metropolitan Area Planning Council...

; and I-93 from Quincy to Manchester, New Hampshire.