Robertsonian translocation
Overview
Robertsonian translocation (ROB) is a common form of chromosomal
rearrangement that in humans occurs in the five acrocentric chromosome pairs, namely 13, 14, 15, 21, and 22. Other translocations occur but do not lead to a viable fetus
. They are named after the American biologist William Rees Brebner Robertson Ph.D. (1881–1941), who first described a Robertsonian translocation in grasshoppers in 1916.
Chromosome
A chromosome is an organized structure of DNA and protein found in cells. It is a single piece of coiled DNA containing many genes, regulatory elements and other nucleotide sequences. Chromosomes also contain DNA-bound proteins, which serve to package the DNA and control its functions.Chromosomes...
rearrangement that in humans occurs in the five acrocentric chromosome pairs, namely 13, 14, 15, 21, and 22. Other translocations occur but do not lead to a viable fetus
Fetus
A fetus is a developing mammal or other viviparous vertebrate after the embryonic stage and before birth.In humans, the fetal stage of prenatal development starts at the beginning of the 11th week in gestational age, which is the 9th week after fertilization.-Etymology and spelling variations:The...
. They are named after the American biologist William Rees Brebner Robertson Ph.D. (1881–1941), who first described a Robertsonian translocation in grasshoppers in 1916.
Unanswered Questions
