Robert Walter Doyne
Encyclopedia
Robert Walter Doyne was a British ophthalmologist. He studied medicine in Oxford
Oxford
The city of Oxford is the county town of Oxfordshire, England. The city, made prominent by its medieval university, has a population of just under 165,000, with 153,900 living within the district boundary. It lies about 50 miles north-west of London. The rivers Cherwell and Thames run through...

, Bristol
Bristol
Bristol is a city, unitary authority area and ceremonial county in South West England, with an estimated population of 433,100 for the unitary authority in 2009, and a surrounding Larger Urban Zone with an estimated 1,070,000 residents in 2007...

 and St. George's Hospital in London
London
London is the capital city of :England and the :United Kingdom, the largest metropolitan area in the United Kingdom, and the largest urban zone in the European Union by most measures. Located on the River Thames, London has been a major settlement for two millennia, its history going back to its...

. In 1886 he founded the Oxford Eye Hospital, and in 1909 became the first president of the Oxford Ophthalmological Congress.

In 1899 Doyne discovered colloid bodies lying on Bruch's membrane
Bruch's membrane
Bruch's membrane is the innermost layer of the choroid. It is also called the vitreous lamina, because of its glassy microscopic appearance.It is 2–4 μm thick.-Layers:Bruch's membrane consists of five layers :...

 that appeared to merge together forming a mosaic pattern that resembled a honeycomb. Afterwards this disorder was referred to as Doyne's honeycomb choroiditis. Today this condition is known to be a rare hereditary form of macular degeneration
Macular degeneration
Age-related macular degeneration is a medical condition which usually affects older adults and results in a loss of vision in the center of the visual field because of damage to the retina. It occurs in “dry” and “wet” forms. It is a major cause of blindness and visual impairment in older adults...

 which results in progressive and irreversible loss of vision, and goes by several names such as macula
Macula
The macula or macula lutea is an oval-shaped highly pigmented yellow spot near the center of the retina of the human eye. It has a diameter of around 5 mm and is often histologically defined as having two or more layers of ganglion cells...

r drusen
Drusen
Drusen are tiny yellow or white accumulations of extracellular material that build up in Bruch's membrane of the eye. The presence of a few small drusen is normal with advancing age, and most people over 40 have some hard drusen...

, malattia leventinese, dominant radial drusen and Doyne honeycomb retina
Retina
The vertebrate retina is a light-sensitive tissue lining the inner surface of the eye. The optics of the eye create an image of the visual world on the retina, which serves much the same function as the film in a camera. Light striking the retina initiates a cascade of chemical and electrical...

l dystrophy.

In 1889 Doyne was the first physician to describe angioid streaks
Angioid streaks
Angioid streaks, also called Knapp streaks or Knapp striae are small breaks in Bruch's membrane, an elastic tissue containing membrane of the retina that can become calcified and crack....

, a disorder that affects Bruch's membrane. Two years after his death in 1916, the "Doyne Memorial Lecture" was established, which is a prized distinction in British Ophthalmology.
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