Ranimustine
Encyclopedia
Ranimustine is a nitrosourea alkylating agent
approved in Japan
for the treatment of chronic myelogenous leukemia
and polycythemia vera.
It has never been filed for FDA
evaluation in the United States
, where it is not marketed.
Alkylating antineoplastic agent
An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group to DNA.The alkyl group is attached to the guanine base of DNA, at the number 7 nitrogen atom of the purine ring....
approved in Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...
for the treatment of chronic myelogenous leukemia
Leukemia
Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...
and polycythemia vera.
It has never been filed for FDA
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
evaluation in the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
, where it is not marketed.