Radiation-induced erythema multiforme
Encyclopedia
Radiation-induced erythema multiforme
may occur when phenytoin
is given prophylactically to neurosurgical patients who are receiving whole-brain therapy and systemic steroids.
Erythema multiforme
Erythema multiforme is a skin condition of unknown cause, possibly mediated by deposition of immune complex in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure...
may occur when phenytoin
Phenytoin
Phenytoin sodium is a commonly used antiepileptic. Phenytoin acts to suppress the abnormal brain activity seen in seizure by reducing electrical conductance among brain cells by stabilizing the inactive state of voltage-gated sodium channels...
is given prophylactically to neurosurgical patients who are receiving whole-brain therapy and systemic steroids.