Rac (GTPase)
Encyclopedia
Rac is a subfamily of the Rho family of GTPases
, small (~21 kDa) signaling G protein
s (more specifically a GTPase
s).
The subgroup include:
Rho family of GTPases
The Rho family of GTPases is a family of small signaling G protein , and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have been shown to regulate many aspects of intracellular actin dynamics, and are found in all eukaryotic organisms including yeasts and some plants...
, small (~21 kDa) signaling G protein
G protein
G proteins are a family of proteins involved in transmitting chemical signals outside the cell, and causing changes inside the cell. They communicate signals from many hormones, neurotransmitters, and other signaling factors. G protein-coupled receptors are transmembrane receptors...
s (more specifically a GTPase
GTPase
GTPases are a large family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate . The GTP binding and hydrolysis takes place in the highly conserved G domain common to all GTPases.-Functions:...
s).
The subgroup include:
- Rac1RAC1Ras-related C3 botulinum toxin substrate 1 also known as Rac1 is a protein that in humans is encoded by the RAC1 gene. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.- Function :Rac1 is...
- Rac2Rac2Rac2 is a small signaling G protein , and is a member of the Rac subfamily of the family Rho family of GTPases...
- Rac3Rac3Rac3 is a small monomeric GTP-binding protein G protein and is an important component of intracellular signalling pathways. It is a member of the Rac subfamily of the Rho family of small G proteins and is encoded by the gene RAC3....
- RhoGRhoGRhoG is a small monomeric GTP-binding protein , and is an important component of many intracellular signalling pathways...