RHAG
Encyclopedia
Rh-associated glycoprotein (RHAG) is an ammonia transporter
protein
that in humans is encoded by the RHAG gene
. RHAG has also recently been designated CD241 (cluster of differentiation
241). Mutations in the RHAG gene can cause stomatocytosis
.
Ammonia transporter
Ammonia transporters are structurally related membrane transport proteins called Amt proteins , methylammonium/ammonium permeases or RhAG, RhBG, and RhCG Rh family members in mammals. The RhAG, RhBG and RhCG proteins constitute solute carrier family 42...
protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the RHAG gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. RHAG has also recently been designated CD241 (cluster of differentiation
Cluster of differentiation
The cluster of differentiation is a protocol used for the identification and investigation of cell surface molecules present on white blood cells, providing targets for immunophenotyping of cells...
241). Mutations in the RHAG gene can cause stomatocytosis
Hereditary stomatocytosis
Hereditary stomatocytosis describes a number of inherited autosomal dominant human conditions which affect the red blood cell, in which the membrane or outer coating of the cell 'leaks' sodium and potassium ions.-Pathophysiology:...
.