RAD17
Encyclopedia
Cell cycle checkpoint protein RAD17 is a protein
that in humans is encoded by the RAD17 gene
.
with RAD9A
, RAD1 homolog
, POLE
, NHP2L1
, Ataxia telangiectasia mutated
, HUS1
and Ataxia telangiectasia and Rad3 related
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the RAD17 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
RAD17 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with RAD9A
RAD9A
Cell cycle checkpoint control protein RAD9A is a protein that in humans is encoded by the RAD9A gene.-Interactions:RAD9A has been shown to interact with RAD17, HDAC1, TOPBP1, RAD1 homolog, BCL2-like 1, Bcl-2, Androgen receptor, DNAJC7, HUS1 and Abl gene.-Further reading:...
, RAD1 homolog
RAD1 homolog
Cell cycle checkpoint protein RAD1 is a protein that in humans is encoded by the RAD1 gene.-Interactions:RAD1 homolog has been shown to interact with RAD9A, RAD17 and HUS1.-Further reading:...
, POLE
POLE
DNA polymerase epsilon catalytic subunit A is an enzyme that in humans is encoded by the POLE gene.-Further reading:...
, NHP2L1
NHP2L1
NHP2-like protein 1 is a protein that in humans is encoded by the NHP2L1 gene.-Further reading:...
, Ataxia telangiectasia mutated
Ataxia telangiectasia mutated
Ataxia telangiectasia mutated is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis...
, HUS1
HUS1
Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.-Interactions:HUS1 has been shown to interact with RAD9A, RAD17, HDAC1, RAD1 homolog and PCNA.-Further reading:...
and Ataxia telangiectasia and Rad3 related
Ataxia telangiectasia and Rad3 related
Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein or FRAP-related protein 1 is an enzyme that in humans is encoded by the ATR gene...
.