Pulmonary surfactant-associated protein C
Encyclopedia
Pulmonary surfactant-associated protein C is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the SFTPC gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

.

Pulmonary surfactant-associated protein C is a membrane protein
Membrane protein
A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. More than half of all proteins interact with membranes.-Function:...

 which manufactures surfactant.

Clinical significance

It is associated with Surfactant metabolism dysfunction
Surfactant metabolism dysfunction
Surfactant metabolism dysfunction is a condition where pulmonary surfactant is insufficient for adequate respiration.Types include:...

type 2.

Humans and animals born lacking SP-C tend to develop progressive interstitial pneumonitis.

Further reading

External links

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