Pseudodominance
Encyclopedia
Pseudodominance is the situation in which the inheritance of an autosomal recessive trait mimics an autosomal dominant pattern.

The pattern of inheritance in which the recessive allele could give its expression in absence of its dominant allele is known as pseudodominance. Haemophilia and colour blindness are the genetic disease due to X linked recessive allele giving their expression in human male is pseudodominance and in human female is dominance.

Pseudodominance also observed in autosomal recessive condition in subsequent generations .This could happen in the case of loss of genetic material from one homolog bearing the dominant allele. The heterozygous condition is therefore lost at that particular locus and the recessive phenotype is revealed.

See also

  • Central dogma of molecular biology
    Central dogma of molecular biology
    The central dogma of molecular biology was first articulated by Francis Crick in 1958 and re-stated in a Nature paper published in 1970:In other words, the process of producing proteins is irreversible: a protein cannot be used to create DNA....


Note: Hemophilia and Colorblindness are sex-linked RECESSIVE traits.

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