Prostaglandin E2 receptor
Encyclopedia
Prostaglandin E2 receptor (53kDa), also known as EP2, is a prostaglandin receptor
for prostaglandin E2. It is encoded by the human gene
PTGER2.
It may be associated with aspirin-induced asthma.
Gs
.
Prostaglandin receptor
There are currently ten known prostaglandin receptors on various cell types. Prostaglandins bind to a subfamily of cell surface seven-transmembrane receptors, G-protein-coupled receptors.These receptors are named:* DP1-2 - DP1, DP2 receptors...
for prostaglandin E2. It is encoded by the human gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
PTGER2.
It may be associated with aspirin-induced asthma.
Mechanism
The receptor is a G-protein coupled receptor, which activates the G proteinG protein
G proteins are a family of proteins involved in transmitting chemical signals outside the cell, and causing changes inside the cell. They communicate signals from many hormones, neurotransmitters, and other signaling factors. G protein-coupled receptors are transmembrane receptors...
Gs
Gs alpha subunit
The Gs alpha subunit is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylate cyclase.-Receptors:The G protein-coupled receptors that couple to this kind of G-protein include:...
.