Promega
Encyclopedia
Promega Corporation
Type Private
Founded 1978 Madison, Wisconsin as Biotec
Location Fitchburg, Wisconsin
Fitchburg, Wisconsin
Fitchburg is a city in Dane County, Wisconsin, United States. The population was 25,260 at the 2010 census. Fitchburg is a suburb of Madison and is part of the Madison Metropolitan Statistical Area.-History:...

 headquarters
Key people William A. Linton Chairman and CEO
Industry
Industry
Industry refers to the production of an economic good or service within an economy.-Industrial sectors:There are four key industrial economic sectors: the primary sector, largely raw material extraction industries such as mining and farming; the secondary sector, involving refining, construction,...

Biotechnology
Biotechnology
Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bioproducts. Biotechnology also utilizes these products for manufacturing purpose...

Revenue
Revenue
In business, revenue is income that a company receives from its normal business activities, usually from the sale of goods and services to customers. In many countries, such as the United Kingdom, revenue is referred to as turnover....

$220 million USD (2007)
Employees ~950 worldwide (2008)
Website
Website
A website, also written as Web site, web site, or simply site, is a collection of related web pages containing images, videos or other digital assets. A website is hosted on at least one web server, accessible via a network such as the Internet or a private local area network through an Internet...

http://www.promega.com/

Promega Corporation is a manufacturer of enzymes and other products for biotechnology and molecular biology.

History

Promega Corporation was founded by Bill Linton in 1978 to provide restriction enzymes for biotechnology. The company now offers more than 2,000 life science products .
The privately held company has its headquarters in Fitchburg, WI with branch offices in 13 countries and manufacturing facilities in San Luis Obispo, California, USA; Shanghai, China; and Seoul, South Korea. Promega Corporation also established the first biotechnology joint venture in China (Sino-American Biotechnology Co. in 1985).

As of 2008, 145 US patents and a number of foreign patents were assigned to the company. In addition to developing its own intellectual property, the company works with academic institutions including the Wisconsin Alumni Research Foundation Research Tool Subscription Program.

The company has developed an on-site stocking system, which uses radio frequency identification (RFID) linked to the internet to track and manage remote inventory. This resulted in the spin-off company Terso Solutions
Terso Solutions
Terso Solutions, Inc., located in Madison, Wisconsin, USA, is the developer and distributor of an automated system for storage and distribution of high value research reagents and medical supplies. Terso has developed a [reagent stocking system, which uses radio frequency identification tags along...

 that specializes in the design and manufacture of small RFID storage units .

Genomics

The company's portfolio began with products for genomics researchers and now includes cloning systems, luciferase reporters, and amplification products as well as the original restriction and modifying enzymes. The portfolio of amplification products includes the GoTaq family of polymerases and buffers and the Plexor quantitative PCR system.

Genetic Identity and Forensics

The company is one of two main suppliers of systems for genetic identification based on DNA analysis using short tandem repeats (STRs),. Promega was the first company to provide kits for STR analysis
STR analysis
Short tandem repeat analysis is a molecular biology method used to compare specific loci on DNA from two or more samples. A short tandem repeat is a microsatellite, consisting of a unit of two to thirteen nucleotides repeated hundreds of times in a row on the DNA strand. STR analysis measures...

of single loci. Along with Applied Biosystems, Promega participated with the FBI and other crime labs in validating STR loci that would eventually be selected as the core loci for the COmbined DNA Index System (CODIS), used for forensic DNA testing in North America.

The Promega PowerPlex STR systems were the first commercially available systems for STR analysis that contained all of the CODIS loci.

Proteomics

The company was an early supplier in the cell-free protein synthesis field and is continuing to develop its portfolio in this area.

Cellular Analysis and Drug Discovery

Promega offers a range of products for cell biology and drug discovery, many of which are built upon bioluminescence technology. Assays for drug discovery are used globally and include biochemical and cell-based assays. In 2010, Promega launched a custom assay services business for biologics and small molecule drug development.

Integrated Platforms

The company's bioluminescence assays, DNA and RNA purification chemistries, and HaloTag technologies integrate with the high-throughput automated systems found in many laboratories. Some of this integration has occurred through collaboration with instrument manufacturers.

The company also sells its own Maxwell 16 System, a bench-top automated purification system for lower throughput research and diagnostic laboratories. .

Promega GloMax Luminometers are supplied with preinstalled protocols that allow researchers to perform multiplex bioluminescent assays. The luminometers with injection systems are available for use with dual-reporter assays like the Dual-Luciferase systems.

The Y-Chromosome Deletion Detection System from Promega also carries the CE Mark for use as an in vitro diagnostic device in the European Union.

External links

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