Premier Biosoft
Encyclopedia
PREMIER Biosoft International (“PBI” for short) is a California
California
California is a state located on the West Coast of the United States. It is by far the most populous U.S. state, and the third-largest by land area...

, United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 based bioinformatics
Bioinformatics
Bioinformatics is the application of computer science and information technology to the field of biology and medicine. Bioinformatics deals with algorithms, databases and information systems, web technologies, artificial intelligence and soft computing, information and computation theory, software...

 company. The company specializes in developing software for use in life science research. In addition to developing software products, the company offers assay design services and consultancy for bioinformatics projects.

Company Background

PREMIER Biosoft, established in 1994, is one of the earliest bioinformatics company, founded by Ms. Kay Brown with a mission to serve the life science research labs all over the world. The mission statement for PBI reads as follows:“Accelerating Research in Life Sciences” The company serves research labs, pharmaceuticals, core facilities and biotechnology companies with its products. The company's first product, Primer Premier, was authored over 12 years ago, for designing PCR assays.

Products & Services

After the launch of Primer Premier
Primer Premier
Primer Premier software combines design of primers for various PCR applications under one common platform. The software supports design of degenerate primers on alignments for amplifying related set of nucleotide sequences for detecting common traits among organisms and to determine heredity. The...

 the company released SimVector, a plasmid drawing and cloning simulation tool, and Array Designer, for designing microarray probes.

The trend in the PCR market was soon shifting towards a new and powerful technique called real time PCR. PREMIER Biosoft caught up early and authored Beacon Designer
Beacon designer
Beacon Designer designs highly specific an efficient primers and probes for real time PCR assays. It is compatible to work on Windows as well as on Mac. The software currently supports the following real time PCR chemistries for efficient primer and probe design.1. SYBR Green 2. TaqMan 3....

, supporting the most popular real time PCR chemistries The company later came out with a pathogen detection system called AlleleID
AlleleID
AlleleID designs oligos for strain differentiation and taxa specific assays. This aids in bacterial identification, pathogen detection and species identification...

 with support for real time PCR and microarray probe design for designing cross species, species specific, intron-exon spanning assays and splice variant microarrays.

The company has ventured into proteomics, glycomics and lipidomics research with the launch of Xpression Primer (tagged primer design tool), SimGlycan (MS/MS data analysis tool) and SimLipid (lipid characterization tool). The company's latest offerings, TMA Foresight, analyzes tissue microarray
Tissue microarray
Tissue microarrays consist of paraffin blocks in which up to 1000 separate tissue cores are assembled in array fashion to allow multiplex histological analysis.-History:...

 data and PrimerPlex
PrimerPlex
PrimerPlex designs oligos for standard multiplex PCR assays and for bead-based suspension array systems such as BioPlex-200 and Luminex 100/200 based on xMAP technology. The assays are used for high-throughput SNP applications such as genotyping, pathogen detection, strain typing, and haplotyping...

, designs oligos for xMAP based multiplex systems.

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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