Posterior polymorphous corneal dystrophy 3
Encyclopedia
Posterior Polymorphous Corneal Dystrophy 3 (PPCD3) is a rare disease of the cornea
. It is linked to the mutations in ZEB1
gene.
Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, with the cornea accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is...
. It is linked to the mutations in ZEB1
ZEB1
Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene.TCF8 encodes a human zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription...
gene.
See also
- Posterior polymorphous corneal dystrophy 1Posterior polymorphous corneal dystrophy 1Posterior Polymorphous Corneal Dystrophy 1 is a rare disease of the cornea, characterised by changes in Descemet's membrane and endothelial layer. Symptoms mainly consist of decreased vision due to corneal edema. In some cases they are present from birth, other patients are asymptomatic...
- Posterior polymorphous corneal dystrophy 2Posterior polymorphous corneal dystrophy 2Posterior Polymorphous Corneal Dystrophy 2 is a rare disease of the cornea. It is linked to the mutations in COL8A2.-See also:*Posterior polymorphous corneal dystrophy 1*Posterior polymorphous corneal dystrophy 3-External links:...
External links
- Posterior Polymorphous Corneal Dystrophy at eMedicineEMedicineeMedicine is an online clinical medical knowledge base that was founded in 1996 by Scott Plantz and Richard Lavely, two medical doctors. The website is searchable by keyword and consists of approximately 6,800 articles, each of which is associated with one of 62 clinical subspecialty textbooks...