Piperidinedione
Encyclopedia
Piperidinediones are a derivatives of piperidine
Piperidine
Piperidine is an organic compound with the molecular formula 5NH. This heterocyclic amine consists of a six-membered ring containing five methylene units and one nitrogen atom...

 with two ketone
Ketone
In organic chemistry, a ketone is an organic compound with the structure RCR', where R and R' can be a variety of atoms and groups of atoms. It features a carbonyl group bonded to two other carbon atoms. Many ketones are known and many are of great importance in industry and in biology...

 functional group
Functional group
In organic chemistry, functional groups are specific groups of atoms within molecules that are responsible for the characteristic chemical reactions of those molecules. The same functional group will undergo the same or similar chemical reaction regardless of the size of the molecule it is a part of...

s. There are six isomer
Isomer
In chemistry, isomers are compounds with the same molecular formula but different structural formulas. Isomers do not necessarily share similar properties, unless they also have the same functional groups. There are many different classes of isomers, like stereoisomers, enantiomers, geometrical...

s, each of which has a molecular weight of 113.115 and a formula of C5H7NO2. Piperidinediones form the core structure of a variety of pharmaceutical drug
Medication
A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease.- Classification :...

s.

Isomers

  • 2,3-Piperidinedione
  • 2,4-Piperidinedione -
    • Examples include]] methyprylon
      Methyprylon
      Methyprylon is a sedative of the piperidinedione derivative family developed by Hoffmann-La Roche.This medicine was used for treating insomnia, but is now rarely used as it has been replaced by newer drugs with fewer side effects, such as benzodiazepines.Methyprylon was withdrawn from the US...

  • 2,5-Piperidinedione -
  • 2,6-Piperidinedione -
    • Examples include glutethimide
      Glutethimide
      Glutethimide is a hypnotic sedative that was introduced in 1954 as a safe alternative to barbiturates to treat insomnia. Before long, however, it had become clear that glutethimide was just as likely to cause addiction and caused similarly severe withdrawal symptoms...

       and dexetimide
      Dexetimide
      Dexetimide is a piperidine anticholinergic. It is a muscarinic antagonist that has been used to treat neuroleptic-induced Parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968....

  • 3,4-Piperidinedione
  • 3,5-Piperidinedione
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