Pharmaceutical Product Development
Encyclopedia
Pharmaceutical Product Development (PPD, Inc.) is a leading global contract research organization
Contract research organization
A contract research organization, also called a clinical research organization, is a service organization that provides support to the pharmaceutical and biotechnology industries in the form of outsourced pharmaceutical research services...

 (CRO) providing discovery, development and post-approval services as well as compound partnering programs. The company’s clients and partners include pharmaceutical, biotechnology, medical device, academic and government organizations. While PPD is mainly known for conducting all aspects of drug development for its clients, it also invests directly in developing new products through its compound partnering program.

History

PPD was founded by Fred Eshelman, Pharm.D., as a one-person consulting firm in 1985. The following year he expanded the company's scope to include development services and relocated operations from Maryland to North Carolina.

Location

PPD is headquartered in Wilmington, N.C. The company has approximately 11,000 employees in 48 countries.

Operations

PPD operates in two main segments: development services and discovery sciences/compound partnering. PPD has also forged strategic alliances with various biopharmaceutical companies and consulting firms in key areas of drug development.

Development Services

PPD provides clinical development and post-approval services for biopharmaceuticals and devices. In addition to offering full service Phase II-IIIb clinical studies for multinational regulatory submissions, PPD provides bioanalytical, cGMP product analysis, global central laboratory, and vaccines and biologics lab services. PPD has a 300-bed healthy volunteer (Phase I) clinic and a dental research clinic in Austin, Texas.

The company’s post-approval services include epidemiology, risk management and outcomes research; late-stage trials; medical information; product safety; registries and observational studies.

PPD offers also clinical data management and information solutions, including consulting and proprietary software tools to speed collection, analysis and reporting of clinical data.

Discovery Sciences/Compound Partnering

The discovery sciences segment offers biomarker discovery services, nonclinical development and preclinical services.[6]Through its compound partnering program, it also seeks to in-license early-stage compounds, take them through proof of concept, and out-license them to its partners for late clinical testing and commercialization. PPD shares in the risks and rewards of bringing a drug to market, gaining revenues generated by licensing fees, milestone payments and commercial royalties.

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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