Per-protocol analysis
Encyclopedia
In epidemiology
, per-protocol (PP) analysis is a strategy of analysis in which only patients who complete the entire clinical trial
are counted towards the final results. Intention to treat analysis
uses data from all patients, including those who did not complete the study.
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...
, per-protocol (PP) analysis is a strategy of analysis in which only patients who complete the entire clinical trial
Clinical trial
Clinical trials are a set of procedures in medical research and drug development that are conducted to allow safety and efficacy data to be collected for health interventions...
are counted towards the final results. Intention to treat analysis
Intention to treat analysis
In epidemiology, an intention to treat analysis is an analysis based on the initial treatment intent, not on the treatment eventually administered. ITT analysis is intended to avoid various misleading artifacts that can arise in intervention research...
uses data from all patients, including those who did not complete the study.
External links
- Per-protocol analysis - Glossary of the Nature Clinical PracticeNature Clinical PracticeNature Clinical Practice may refer to any of the following journals:* Nature Reviews Cardiology* Nature Reviews Endocrinology* Nature Reviews Gastroenterology & Hepatology* Nature Reviews Nephrology* Nature Reviews Neurology...
- Intent-to-treat versus on treatment analysis: how to interpret the results of a clinical trial?