Pegaspargase
Encyclopedia
Pegaspargase is a modified enzyme
used as an antineoplastic agent. It is a form of L-asparaginase which has undergone PEGylation
.
It is used in the treatment of acute lymphoblastic leukemia
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
used as an antineoplastic agent. It is a form of L-asparaginase which has undergone PEGylation
PEGylation
PEGylation is the process of covalent attachment of polyethylene glycol polymer chains to another molecule, normally a drug or therapeutic protein. PEGylation is routinely achieved by incubation of a reactive derivative of PEG with the target macromolecule...
.
It is used in the treatment of acute lymphoblastic leukemia
Acute lymphoblastic leukemia
Acute lymphoblastic leukemia is a form of leukemia, or cancer of the white blood cells characterized by excess lymphoblasts.Malignant, immature white blood cells continuously multiply and are overproduced in the bone marrow. ALL causes damage and death by crowding out normal cells in the bone...
.