PRIMA1
Encyclopedia
Proline-rich membrane anchor 1, also known as PRiMA, is a protein
that in humans is encoded by the PRIMA1 gene
. PRiMA functions to organize acetylcholinesterase
(AChE) into tetramers, and to anchor AChE at neural cell membranes.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the PRIMA1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. PRiMA functions to organize acetylcholinesterase
Acetylcholinesterase
"Acetylcholinesterase, also known as AChE or acetylcholine acetylhydrolase, is an enzyme that degrades the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic nervous system, where its activity serves to terminate...
(AChE) into tetramers, and to anchor AChE at neural cell membranes.