PPP1CA
Encyclopedia
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that in humans is encoded by the PPP1CA gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Interactions

PPP1CA has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with LMTK2
LMTK2
Serine/threonine-protein kinase LMTK2 also known as Lemur tyrosine kinase 2 is an enzyme that in humans is encoded by the LMTK2 gene.- Function :...

, PPP1R15A
PPP1R15A
Protein phosphatase 1 regulatory subunit 15A is an enzyme that in humans is encoded by the PPP1R15A gene.-Interactions:PPP1R15A has been shown to interact with PPP1CB, PPP1CA, PPP1CC, SMARCB1, LYN, TSN, BAG1 and MLL.-Further reading:...

, AKAP11
AKAP11
A-kinase anchor protein 11 is an enzyme that in humans is encoded by the AKAP11 gene.-Interactions:AKAP11 has been shown to interact with PPP1CA, GSK3B, PRKAR2A and PRKAR2B.-Further reading:...

, Host cell factor C1
Host cell factor C1
Host cell factor is a protein that in humans is encoded by the HCFC1 gene.-Interactions:Host cell factor C1 has been shown to interact with HDAC1, Histone deacetylase 2, OGT, SIN3A, SUDS3, ZBTB17, Sp1 transcription factor, MLL, PPP1CA, POU2F1, PDCD2, WDR5, CREB3 and GABPA.-Further reading:...

, PHACTR3
PHACTR3
Phosphatase and actin regulator 3 is an enzyme that in humans is encoded by the PHACTR3 gene.-Further reading:...

, Protein kinase R
Protein kinase R
Protein kinase RNA-activated also known as protein kinase R , interferon-induced, double-stranded RNA-activated protein kinase, or eukaryotic translation initiation factor 2-alpha kinase 2 is an enzyme that in humans is encoded by the EIF2AK2 gene.PKR protects against viral...

, BCL2-like 1
BCL2-like 1 (gene)
Bcl-2-like protein 1 is a protein that in humans is encoded by the BCL2L1 gene.-Interactions:BCL2-like 1 has been shown to interact with RAD9A, RTN1, BAK1, Reticulon 4, Bcl-2-associated X protein, BCAP31, Bcl-2-interacting killer, PPP1CA, Noxa, VDAC1, BCL2L11, Bcl-2-associated death promoter,...

, BCL2L2
BCL2L2
Bcl-2-like protein 2 is a protein that in humans is encoded by the BCL2L2 gene.This gene encodes a pro-survival member of the bcl-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown...

, CDC5L
CDC5L
Cell division cycle 5-like protein is a protein that in humans is encoded by the CDC5L gene.-Interactions:CDC5L has been shown to interact with SRRM1, RPS25, SF3B1, ILF2, CWC15, DNA-PKcs, GCN1L1, BZW1, TTF2, SF3B2, SFRS2, ASF/SF2, PLRG1, DYNC1H1, PPP1CA, Small nuclear ribonucleoprotein D1, SF3B4,...

, PPP1R8
PPP1R8
Nuclear inhibitor of protein phosphatase 1 is an enzyme that in humans is encoded by the PPP1R8 gene.-Interactions:PPP1R8 has been shown to interact with PPP1CA, Histone deacetylase 2, SF3B1 and EED.-Further reading:...

, SMARCB1
SMARCB1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 is a protein that in humans is encoded by the SMARCB1 gene.-Interactions:...

, KvLQT1
KvLQT1
Kv7.1 is a potassium channel protein coded for by the gene KCNQ1. Kv7.1 is present in the cell membranes of cardiac muscle tissue and in inner ear neurons among other tissues...

, BRCA1
BRCA1
BRCA1 is a human caretaker gene that produces a protein called breast cancer type 1 susceptibility protein, responsible for repairing DNA. The first evidence for the existence of the gene was provided by the King laboratory at UC Berkeley in 1990...

 and PPP1R9B
PPP1R9B
Neurabin-2 is a protein that in humans is encoded by the PPP1R9B gene.-Interactions:PPP1R9B has been shown to interact with PPP1CB, PPP1CA, Dopamine receptor D2, P16, PPP1CC, T-cell lymphoma invasion and metastasis-inducing protein 1 and PPP1R2....

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Further reading

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