PLoS Computational Biology is a peer-reviewed

Peer review

Peer review is a process of self-regulation by a profession or a process of evaluation involving qualified individuals within the relevant field. Peer review methods are employed to maintain standards, improve performance and provide credibility...

 computational biology

Computational biology

Computational biology involves the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems...

 journal established in 2005 and published by the nonprofit Public Library of Science

Public Library of Science

The Public Library of Science is a nonprofit open-access scientific publishing project aimed at creating a library of open access journals and other scientific literature under an open content license...

 in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne

Philip Bourne

Philip Eric Bourne is a professor of pharmacology at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego ....

. All articles are open access

Open access

Open access refers to unrestricted access via the Internet to articles published in scholarly journals, and also increasingly to book chapters or monographs....

 and licensed under the Creative Commons Attribution License

Creative Commons licenses

Creative Commons licenses are several copyright licenses that allow the distribution of copyrighted works. The licenses differ by several combinations that condition the terms of distribution. They were initially released on December 16, 2002 by Creative Commons, a U.S...

.
The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia.