PCBP2
Encyclopedia
Poly-binding protein 2 is a protein
that in humans is encoded by the PCBP2 gene
.
In humans, the PCBP2 gene overlaps with TUC338
, a transcribed ultra-conserved element
implicated in Hepatocellular carcinoma
.
with HNRPK
, PTBP1
and HNRNPL
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the PCBP2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
In humans, the PCBP2 gene overlaps with TUC338
TUC338
TUC338 is an ultra-conserved element which is transcribed to give a non-coding RNA. The TUC338 gene was first identified as uc.338, along with 480 other ultra-conserved elements in the human genome...
, a transcribed ultra-conserved element
Ultra-conserved element
An ultra-conserved element is a region of human DNA of length 200 nucleotides or greater, which is entirely conserved in both rats and mice...
implicated in Hepatocellular carcinoma
Hepatocellular carcinoma
Hepatocellular carcinoma is the most common type of liver cancer. Most cases of HCC are secondary to either a viral hepatitide infection or cirrhosis .Compared to other cancers, HCC is quite a rare tumor in the United States...
.
Interactions
PCBP2 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with HNRPK
HNRPK
Heterogeneous nuclear ribonucleoprotein K is a protein that in humans is encoded by the HNRNPK gene.-Interactions:HNRPK has been shown to interact with KHDRBS1, PCBP2, PTBP1, DDX1, PRMT1, HNRNPL and C-src tyrosine kinase.-Further reading:...
, PTBP1
PTBP1
Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene.-Interactions:PTBP1 has been shown to interact with HNRPK, PCBP2, SFPQ and HNRNPL.This gene is targeted by the microRNA miR-124...
and HNRNPL
HNRNPL
Heterogeneous nuclear ribonucleoprotein L is a protein that in humans is encoded by the HNRNPL gene.-Interactions:HNRNPL has been shown to interact with PCBP2, HNRPK and PTBP1.-Further reading:...
.