PAFAH1B1
Encyclopedia
Platelet-activating factor acetylhydrolase IB subunit alpha is an enzyme
that in humans is encoded by the PAFAH1B1 gene
.
According to one study, PAFAH1B1 interacts with VLDLR receptor activated by reelin
.
with DYNC1H1
, CLIP1
, NDEL1
, PAFAH1B3
, PAFAH1B2
, NUDC
, TUBA1A
and Doublecortin
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the PAFAH1B1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
According to one study, PAFAH1B1 interacts with VLDLR receptor activated by reelin
Reelin
Reelin is a large secreted extracellular matrix protein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell–cell interactions. Besides this important role in early development, reelin continues to work in the adult brain. It modulates the...
.
Genomics
The gene is located at chromosome 17p13.3 on the Watson (plus) strand. The gene is 91,953 bases in length and encodes a protein of 410 amino acids (predicted molecular weight 46.638 kiloDaltons).Interactions
PAFAH1B1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with DYNC1H1
DYNC1H1
Cytoplasmic dynein 1 heavy chain 1 is a protein that in humans is encoded by the DYNC1H1 gene.-Interactions:DYNC1H1 has been shown to interact with PAFAH1B1 and CDC5L.-Further reading:...
, CLIP1
CLIP1
CAP-GLY domain containing linker protein 1, also known as CLIP1, is a protein which in humans is encoded by the CLIP1 gene.-Interactions:CLIP1 has been shown to interact with IQGAP1, Mammalian target of rapamycin and PAFAH1B1.-Further reading:...
, NDEL1
NDEL1
Nuclear distribution protein nudE-like 1 is a protein that in humans is encoded by the NDEL1 gene.This gene encodes a thiol-activated oligopeptidase that is phosphorylated in M phase of the cell cycle...
, PAFAH1B3
PAFAH1B3
Platelet-activating factor acetylhydrolase IB subunit gamma is an enzyme that in humans is encoded by the PAFAH1B3 gene.-Interactions:PAFAH1B3 has been shown to interact with PAFAH1B1 and LNX1.-Further reading:...
, PAFAH1B2
PAFAH1B2
Platelet-activating factor acetylhydrolase IB subunit beta is an enzyme that in humans is encoded by the PAFAH1B2 gene.-Interactions:PAFAH1B2 has been shown to interact with PAFAH1B1.-Further reading:...
, NUDC
NUDC
Nuclear migration protein nudC is a protein that in humans is encoded by the NUDC gene.-Interactions:NUDC has been shown to interact with PLK1 and PAFAH1B1.-Further reading:...
, TUBA1A
TUBA1A
Tubulin alpha-1A chain is a protein that in humans is encoded by the TUBA1A gene.-Interactions:TUBA1A has been shown to interact with PAFAH1B1.-Further reading:...
and Doublecortin
Doublecortin
Doublecortex; lissencephaly, X-linked , also known as DCX, is a gene.Doublecortin is a microtubule-associated protein expressed by neuronal precursor cells and immature neurons in embryonic and adult cortical structures...
.