In the parathyroid gland

Parathyroid gland

The parathyroid glands are small endocrine glands in the neck that produce parathyroid hormone. Humans usually have four parathyroid glands, which are usually located on the rear surface of the thyroid gland, or, in rare cases, within the thyroid gland itself or in the chest...

, the parathyroid oxyphil cell is larger and paler than the parathyroid chief cell

Parathyroid chief cell

Parathyroid chief cells are cells in the parathyroid glands which produce parathyroid hormone....

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These cells can be found in clusters in the center of the section and at the periphery. Oxyphil cells appear at the onset of puberty, but have no known function. With nuclear medicine

Nuclear medicine

In nuclear medicine procedures, elemental radionuclides are combined with other elements to form chemical compounds, or else combined with existing pharmaceutical compounds, to form radiopharmaceuticals. These radiopharmaceuticals, once administered to the patient, can localize to specific organs...

 scans, they selectively take up the Technetium

Technetium

Technetium is the chemical element with atomic number 43 and symbol Tc. It is the lowest atomic number element without any stable isotopes; every form of it is radioactive. Nearly all technetium is produced synthetically and only minute amounts are found in nature...

-sestamibi

Sestamibi

Technetium sestamibi is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex of the radioisotope technetium-99m with the ligand methoxyisobutylisonitrile . The generic drug became available late September 2008...

complex radiotracer dye to allow delineation of glandular anatomy.