Orteronel
Encyclopedia
Orteronel is an experimental drug for the treatment of cancer under development by Millennium Pharmaceuticals
. It is currently in Phase III clinical trials for metastatic, hormone-refractory prostate cancer.
Orteronel is an inhibitor
of the enzyme CYP17A1.
Millennium Pharmaceuticals
Millennium Pharmaceuticals, Inc., The Takeda Oncology Company is a biopharmaceutical company based in Cambridge, Massachusetts. The Company markets Velcade for injection, a cancer product, and has a growing clinical development pipeline of product candidates...
. It is currently in Phase III clinical trials for metastatic, hormone-refractory prostate cancer.
Orteronel is an inhibitor
Enzyme inhibitor
An enzyme inhibitor is a molecule that binds to enzymes and decreases their activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used as herbicides and pesticides...
of the enzyme CYP17A1.