Oddball paradigm
Encyclopedia
The oddball paradigm is a technique used in evoked potential
Evoked potential
An evoked potential is an electrical potential recorded from the nervous system of a human or other animal following presentation of a stimulus, as distinct from spontaneous potentials as detected by electroencephalography or electromyography .Evoked potential amplitudes tend to be low, ranging...

 research in which trains of stimuli that are usually auditory or visual are used to assess the neural reactions to unpredictable but recognizable events. The subject is asked to react either by counting or by button pressing incidences of target stimuli that are hidden as rare occurrences amongst a series of more common stimuli, that often require no response. It has been found that an evoked research potential across the parieto-central area of the skull that is usually around 300 ms and called P300
P300
The P300 wave is an event related potential elicited by infrequent, task-relevant stimuli. It is considered to be an endogenous potential as its occurrence links not to the physical attributes of a stimulus but to a person's reaction to the stimulus. More specifically, the P300 is thought to...

 is larger after the target stimulus.

It was first used by Nancy Squires, Kenneth Squires and Steven Hillyard at the University of California, San Diego
University of California, San Diego
The University of California, San Diego, commonly known as UCSD or UC San Diego, is a public research university located in the La Jolla neighborhood of San Diego, California, United States...

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